ArticleCardiovascular diagnosis and therapy2015
Beam hardening artifact reduction using dual energy computed tomography: implications for myocardial perfusion studies.
Article in Cardiovascular diagnosis and therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 30 citations in OpenAlex.
- State of the art of CT myocardial perfusion.La Radiologia medica · 2025Review
- How to perform and evaluate a myocardial perfusion imaging by computed tomography.European heart journal. Imaging methods and practice · 2025Review
- Stereotactic Body Radiation Therapy (SBRT) in prostate cancer in the presence of hip prosthesis - is it a contraindication? A narrative review.BMC urology · 2024Review
- [Beyond Coronary CT Angiography: CT Fractional Flow Reserve and Perfusion].Taehan Yongsang Uihakhoe chi · 2022Review
- Dual-Energy Heart CT: Beyond Better Angiography-Review.Journal of clinical medicine · 2021Review
- Dual-energy CT and coronary imaging.Cardiovascular diagnosis and therapy · 2020Review
- Computed tomographic evaluation of myocardial ischemia.Japanese journal of radiology · 2020Review
- Functional Information in Coronary Artery Disease: The Case of Computed Tomography Myocardial Perfusion.Current cardiology reports · 2017Review
- Myocardial ischemia testing with computed tomography: emerging strategies.Cardiovascular diagnosis and therapy · 2017Review
- Delayed enhancement cardiac computed tomography for the assessment of myocardial infarction: from bench to bedside.Cardiovascular diagnosis and therapy · 2017Review
- Myocardial CT perfusion imaging for ischemia detection.Cardiovascular diagnosis and therapy · 2017Review
- Quantitative evaluation of beam-hardening artefact correction in dual-energy CT myocardial perfusion imaging.European radiology · 2016Article
- Update on Computed Tomography Myocardial Perfusion Imaging.Current cardiovascular imaging reports · 2016Article
- Cardiac CT Imaging of Plaque Vulnerability: Hype or Hope?Current cardiology reports · 2016Review
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Authors and funding
7 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundMyocardial computed tomography perfusion (CTP) using conventional single energy (SE) imaging is influenced by the presence of beam hardening artifacts (BHA), occasionally resembling perfusion defects and commonly observed at the left ventricular posterobasal wall (PB). We therefore sought to explore the ability of dual energy (DE) CTP to attenuate the presence of BHA.
methodsConsecutive patients without history of coronary artery disease who were referred for computed tomography coronary angiography (CTCA) due to atypical chest pain and a normal stress-rest SPECT and had absence or mild coronary atherosclerosis constituted the study population. The study group was acquired using DE and the control group using SE imaging.
resultsDemographical characteristics were similar between groups, as well as the heart rate and the effective radiation dose. Myocardial signal density (SD) levels were evaluated in 280 basal segments among the DE group (140 PB segments for each energy level from 40 to 100 keV; and 140 reference segments), and in 40 basal segments (at the same locations) among the SE group. Among the DE group, myocardial SD levels and myocardial SD ratio evaluated at the reference segment were higher at low energy levels, with significantly lower SD levels at increasing energy levels. Myocardial signal-to-noise ratio was not significantly influenced by the energy level applied, although 70 keV was identified as the energy level with the best overall signal-to-noise ratio. Significant differences were identified between the PB segment and the reference segment among the lower energy levels, whereas at ≥70 keV myocardial SD levels were similar. Compared to DE reconstructions at the best energy level (70 keV), SE acquisitions showed no significant differences overall regarding myocardial SD levels among the reference segments.
conclusionsBHA that influence the assessment of myocardial perfusion can be attenuated using DE at 70 keV or higher.
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