Evidence map›Paper›PMID 25774339›Full record

ArticleCurrent pharmacology reports2015

MicroRNA Regulating Glutathione S-Transferase P1 in Prostate Cancer.

Savita Singh, Girish C Shukla, Sanjay Gupta

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current pharmacology reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Emerging role of miRNAs in the regulation of ferroptosis.Frontiers in molecular biosciences · 2023
    Review
  3. Review
  4. Article
  5. Missing link between microRNA and prostate cancer.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Savita SinghCenter for Gene Regulation in Health and Disease, Cleveland State University, Cleveland, Ohio, USA ; Department of Biological, Geological, and Environmental Sciences, Cleveland State University, Cleveland, Ohio, USA.
Girish C ShuklaCenter for Gene Regulation in Health and Disease, Cleveland State University, Cleveland, Ohio, USA ; Department of Biological, Geological, and Environmental Sciences, Cleveland State University, Cleveland, Ohio, USA.
Sanjay GuptaDepartment of Urology, Case Western Reserve University & University Hospitals Case Medical Center, Cleveland, Ohio, USA ; Division of General Medical Sciences, Case Comprehensive Cancer Center, Cleveland, Ohio, USA.
Cleveland State University · USCase Western Reserve University · US

Funding

Prostate Cancer Chemoprevention by ApigeninR01CA108512 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI GUPTA, SANJAY · 2004 to 2014
$2.4M
Molecular Mechanisms of GSTP1 Reactivation by Green Tea PolyphenolsR01CA115491 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI GUPTA, SANJAY · 2007 to 2011
$1.3M
Prevention of Metastasis by Green Tea PolyphenolsR03CA186179 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI GUPTA, SANJAY · 2014 to 2015
$159k
NCI NIH HHS R01 CA108512NCI NIH HHS R01 CA115491NCI NIH HHS R03 CA186179
6 · The paper itself

Abstract

Glutathione S-transferase P1 (GSTP1), an enzyme involved in detoxification process, is frequently inactivated in prostate cancer due to epigenetic modifications. Through

Indexed as

epigeneticsGSTP1miRNAoxidative DNA damageprostate cancer

Identifiers

PMID25774339
PMCPMC4354897
OpenAlexW2078185718

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.