ReviewJournal of thoracic disease2015
Physiology of the pleural space.
Registry-linked trialAbstract readReview
In one paragraph
Review in Journal of thoracic disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02809872 (Ultrasound Estimation of Pleural Effusion in the Sitting Patients), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ultrasound Estimation of Pleural Effusion in the Sitting Patients
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Thoracostomy tube withdrawal during latter phases of expiration or inspiration: a systematic review and meta-analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023Pooled it
- Beyond Drainage: Can Pleural Effusion Naturally Tamponade Tumor Hemorrhage? Literature Review of Hypotheses for Possible Mechanisms.HCA healthcare journal of medicine · 2026Article
- Investigation of the Prevalence of Chronic Pulmonary Effusion Causes and Response to Treatment (Pleurodesis) in Patients.The open respiratory medicine journal · 2025Article
- Clinical Ramifications of Bacterial Aggregation in Pleural Fluid.Infectious disease reports · 2024Article
- Effect of malignant-associated pleural effusion on endothelial viability, motility and angiogenesis in lung cancer.Cancer science · 2020Article
- Comment on "Comparison of Diaphragmatic Stretch Technique and Manual Diaphragm Release Technique on Diaphragmatic Excursion in Chronic Obstructive Pulmonary Disease: A Randomized Crossover Trial".Pulmonary medicine · 2020Article
- TBX2-positive cells represent a multi-potent mesenchymal progenitor pool in the developing lung.Respiratory research · 2019Article
- Malignant Pleural Effusion and Its Current Management: A Review.Medicina (Kaunas, Lithuania) · 2019Review
- Location of Ruptured Bullae in Secondary Spontaneous Pneumothorax.The Korean journal of thoracic and cardiovascular surgery · 2017Article
- Wt1 and β-catenin cooperatively regulate diaphragm development in the mouse.Developmental biology · 2015Article
- Cytological-energy analysis of pleural effusions with predominance of neutrophils.Therapeutic advances in respiratory diseaseArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors.
Charalampos Charalampidis1 Department of Anatomy-Medical School, Democritus University of Thrace, Alex-polis, Greece ; 2 Cardiothoracic Surgery Department, "Evangelismos" Hospital, Athens, Greece ; 3 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 4 Oncology Department, "Interbalkan" European Medical Center, Thessaloniki, Greece ; 5 Oncology Department, "BioMedicine" Private Clinic, Thessaloniki, Greece ; 6 Pulmonary-Oncology, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 7 Thoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Greece ; 8 Surgery Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 9 Pathology Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 10 Oncology Department, "Saint Luke" Private Hospital, Thessaloniki, Greece.
Andrianna Youroukou1 Department of Anatomy-Medical School, Democritus University of Thrace, Alex-polis, Greece ; 2 Cardiothoracic Surgery Department, "Evangelismos" Hospital, Athens, Greece ; 3 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 4 Oncology Department, "Interbalkan" European Medical Center, Thessaloniki, Greece ; 5 Oncology Department, "BioMedicine" Private Clinic, Thessaloniki, Greece ; 6 Pulmonary-Oncology, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 7 Thoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Greece ; 8 Surgery Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 9 Pathology Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 10 Oncology Department, "Saint Luke" Private Hospital, Thessaloniki, Greece.
George Lazaridis1 Department of Anatomy-Medical School, Democritus University of Thrace, Alex-polis, Greece ; 2 Cardiothoracic Surgery Department, "Evangelismos" Hospital, Athens, Greece ; 3 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 4 Oncology Department, "Interbalkan" European Medical Center, Thessaloniki, Greece ; 5 Oncology Department, "BioMedicine" Private Clinic, Thessaloniki, Greece ; 6 Pulmonary-Oncology, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 7 Thoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Greece ; 8 Surgery Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 9 Pathology Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 10 Oncology Department, "Saint Luke" Private Hospital, Thessaloniki, Greece.
Sofia Baka1 Department of Anatomy-Medical School, Democritus University of Thrace, Alex-polis, Greece ; 2 Cardiothoracic Surgery Department, "Evangelismos" Hospital, Athens, Greece ; 3 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 4 Oncology Department, "Interbalkan" European Medical Center, Thessaloniki, Greece ; 5 Oncology Department, "BioMedicine" Private Clinic, Thessaloniki, Greece ; 6 Pulmonary-Oncology, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 7 Thoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Greece ; 8 Surgery Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 9 Pathology Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 10 Oncology Department, "Saint Luke" Private Hospital, Thessaloniki, Greece.
Ioannis Mpoukovinas1 Department of Anatomy-Medical School, Democritus University of Thrace, Alex-polis, Greece ; 2 Cardiothoracic Surgery Department, "Evangelismos" Hospital, Athens, Greece ; 3 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 4 Oncology Department, "Interbalkan" European Medical Center, Thessaloniki, Greece ; 5 Oncology Department, "BioMedicine" Private Clinic, Thessaloniki, Greece ; 6 Pulmonary-Oncology, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 7 Thoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Greece ; 8 Surgery Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 9 Pathology Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 10 Oncology Department, "Saint Luke" Private Hospital, Thessaloniki, Greece.
Vasilis Karavasilis1 Department of Anatomy-Medical School, Democritus University of Thrace, Alex-polis, Greece ; 2 Cardiothoracic Surgery Department, "Evangelismos" Hospital, Athens, Greece ; 3 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 4 Oncology Department, "Interbalkan" European Medical Center, Thessaloniki, Greece ; 5 Oncology Department, "BioMedicine" Private Clinic, Thessaloniki, Greece ; 6 Pulmonary-Oncology, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 7 Thoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Greece ; 8 Surgery Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 9 Pathology Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 10 Oncology Department, "Saint Luke" Private Hospital, Thessaloniki, Greece.
Ioannis Kioumis1 Department of Anatomy-Medical School, Democritus University of Thrace, Alex-polis, Greece ; 2 Cardiothoracic Surgery Department, "Evangelismos" Hospital, Athens, Greece ; 3 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 4 Oncology Department, "Interbalkan" European Medical Center, Thessaloniki, Greece ; 5 Oncology Department, "BioMedicine" Private Clinic, Thessaloniki, Greece ; 6 Pulmonary-Oncology, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 7 Thoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Greece ; 8 Surgery Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 9 Pathology Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 10 Oncology Department, "Saint Luke" Private Hospital, Thessaloniki, Greece.
Georgia Pitsiou1 Department of Anatomy-Medical School, Democritus University of Thrace, Alex-polis, Greece ; 2 Cardiothoracic Surgery Department, "Evangelismos" Hospital, Athens, Greece ; 3 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 4 Oncology Department, "Interbalkan" European Medical Center, Thessaloniki, Greece ; 5 Oncology Department, "BioMedicine" Private Clinic, Thessaloniki, Greece ; 6 Pulmonary-Oncology, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 7 Thoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Greece ; 8 Surgery Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 9 Pathology Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 10 Oncology Department, "Saint Luke" Private Hospital, Thessaloniki, Greece.
Antonis Papaiwannou1 Department of Anatomy-Medical School, Democritus University of Thrace, Alex-polis, Greece ; 2 Cardiothoracic Surgery Department, "Evangelismos" Hospital, Athens, Greece ; 3 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 4 Oncology Department, "Interbalkan" European Medical Center, Thessaloniki, Greece ; 5 Oncology Department, "BioMedicine" Private Clinic, Thessaloniki, Greece ; 6 Pulmonary-Oncology, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 7 Thoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Greece ; 8 Surgery Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 9 Pathology Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 10 Oncology Department, "Saint Luke" Private Hospital, Thessaloniki, Greece.
Anastasia Karavergou1 Department of Anatomy-Medical School, Democritus University of Thrace, Alex-polis, Greece ; 2 Cardiothoracic Surgery Department, "Evangelismos" Hospital, Athens, Greece ; 3 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 4 Oncology Department, "Interbalkan" European Medical Center, Thessaloniki, Greece ; 5 Oncology Department, "BioMedicine" Private Clinic, Thessaloniki, Greece ; 6 Pulmonary-Oncology, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 7 Thoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Greece ; 8 Surgery Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 9 Pathology Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 10 Oncology Department, "Saint Luke" Private Hospital, Thessaloniki, Greece.
Kosmas Tsakiridis1 Department of Anatomy-Medical School, Democritus University of Thrace, Alex-polis, Greece ; 2 Cardiothoracic Surgery Department, "Evangelismos" Hospital, Athens, Greece ; 3 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 4 Oncology Department, "Interbalkan" European Medical Center, Thessaloniki, Greece ; 5 Oncology Department, "BioMedicine" Private Clinic, Thessaloniki, Greece ; 6 Pulmonary-Oncology, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 7 Thoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Greece ; 8 Surgery Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 9 Pathology Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 10 Oncology Department, "Saint Luke" Private Hospital, Thessaloniki, Greece.
Nikolaos Katsikogiannis1 Department of Anatomy-Medical School, Democritus University of Thrace, Alex-polis, Greece ; 2 Cardiothoracic Surgery Department, "Evangelismos" Hospital, Athens, Greece ; 3 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 4 Oncology Department, "Interbalkan" European Medical Center, Thessaloniki, Greece ; 5 Oncology Department, "BioMedicine" Private Clinic, Thessaloniki, Greece ; 6 Pulmonary-Oncology, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 7 Thoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Greece ; 8 Surgery Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 9 Pathology Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 10 Oncology Department, "Saint Luke" Private Hospital, Thessaloniki, Greece.
Eirini Sarika1 Department of Anatomy-Medical School, Democritus University of Thrace, Alex-polis, Greece ; 2 Cardiothoracic Surgery Department, "Evangelismos" Hospital, Athens, Greece ; 3 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 4 Oncology Department, "Interbalkan" European Medical Center, Thessaloniki, Greece ; 5 Oncology Department, "BioMedicine" Private Clinic, Thessaloniki, Greece ; 6 Pulmonary-Oncology, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 7 Thoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Greece ; 8 Surgery Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 9 Pathology Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 10 Oncology Department, "Saint Luke" Private Hospital, Thessaloniki, Greece.
Konstantinos Kapanidis1 Department of Anatomy-Medical School, Democritus University of Thrace, Alex-polis, Greece ; 2 Cardiothoracic Surgery Department, "Evangelismos" Hospital, Athens, Greece ; 3 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 4 Oncology Department, "Interbalkan" European Medical Center, Thessaloniki, Greece ; 5 Oncology Department, "BioMedicine" Private Clinic, Thessaloniki, Greece ; 6 Pulmonary-Oncology, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 7 Thoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Greece ; 8 Surgery Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 9 Pathology Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 10 Oncology Department, "Saint Luke" Private Hospital, Thessaloniki, Greece.
Leonidas Sakkas1 Department of Anatomy-Medical School, Democritus University of Thrace, Alex-polis, Greece ; 2 Cardiothoracic Surgery Department, "Evangelismos" Hospital, Athens, Greece ; 3 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 4 Oncology Department, "Interbalkan" European Medical Center, Thessaloniki, Greece ; 5 Oncology Department, "BioMedicine" Private Clinic, Thessaloniki, Greece ; 6 Pulmonary-Oncology, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 7 Thoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Greece ; 8 Surgery Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 9 Pathology Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 10 Oncology Department, "Saint Luke" Private Hospital, Thessaloniki, Greece.
Ipokratis Korantzis1 Department of Anatomy-Medical School, Democritus University of Thrace, Alex-polis, Greece ; 2 Cardiothoracic Surgery Department, "Evangelismos" Hospital, Athens, Greece ; 3 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 4 Oncology Department, "Interbalkan" European Medical Center, Thessaloniki, Greece ; 5 Oncology Department, "BioMedicine" Private Clinic, Thessaloniki, Greece ; 6 Pulmonary-Oncology, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 7 Thoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Greece ; 8 Surgery Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 9 Pathology Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 10 Oncology Department, "Saint Luke" Private Hospital, Thessaloniki, Greece.
Sofia Lampaki1 Department of Anatomy-Medical School, Democritus University of Thrace, Alex-polis, Greece ; 2 Cardiothoracic Surgery Department, "Evangelismos" Hospital, Athens, Greece ; 3 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 4 Oncology Department, "Interbalkan" European Medical Center, Thessaloniki, Greece ; 5 Oncology Department, "BioMedicine" Private Clinic, Thessaloniki, Greece ; 6 Pulmonary-Oncology, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 7 Thoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Greece ; 8 Surgery Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 9 Pathology Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 10 Oncology Department, "Saint Luke" Private Hospital, Thessaloniki, Greece.
Konstantinos Zarogoulidis1 Department of Anatomy-Medical School, Democritus University of Thrace, Alex-polis, Greece ; 2 Cardiothoracic Surgery Department, "Evangelismos" Hospital, Athens, Greece ; 3 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 4 Oncology Department, "Interbalkan" European Medical Center, Thessaloniki, Greece ; 5 Oncology Department, "BioMedicine" Private Clinic, Thessaloniki, Greece ; 6 Pulmonary-Oncology, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 7 Thoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Greece ; 8 Surgery Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 9 Pathology Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 10 Oncology Department, "Saint Luke" Private Hospital, Thessaloniki, Greece.
Paul Zarogoulidis1 Department of Anatomy-Medical School, Democritus University of Thrace, Alex-polis, Greece ; 2 Cardiothoracic Surgery Department, "Evangelismos" Hospital, Athens, Greece ; 3 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 4 Oncology Department, "Interbalkan" European Medical Center, Thessaloniki, Greece ; 5 Oncology Department, "BioMedicine" Private Clinic, Thessaloniki, Greece ; 6 Pulmonary-Oncology, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 7 Thoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Greece ; 8 Surgery Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 9 Pathology Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 10 Oncology Department, "Saint Luke" Private Hospital, Thessaloniki, Greece.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pleural cavity is created between the 4(th) and 7(th) week of embryologic development. These embryonic components of visceral and parietal pleurae develop different anatomic characteristics with regard to vascular, lymphatic, and nervous supply. There are two layers: a superficial mesothelial cell layer facing the pleural space and an underlying connective tissue layer. The pleura might present inflammatory response and maintenance of the pleural fluid is observed. The latter function is especially important in the mechanical coupling of the lung and chest wall. Fluid is filtered into the pleural space according to the net hydrostatic oncotic pressure gradient. It flows downward along a vertical pressure gradient, presumably determined by hydrostatic pressure and resistance to viscous flow. There also may be a net movement of fluid from the costal pleura to the mediastinal and interlobar regions. In these areas, pleural fluid is resorbed primarily through lymphatic stomata on the parietal pleural surface. In the current review we will present the physiology of the pleural space in a step by step manner.
Indexed as
physiologypleural spacePneumothorax
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Registered trials
NCT02809872ClinicalTrials.gov
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