Evidence map›Paper›PMID 25773446›Full record

ArticleJournal of extracellular vesicles2015

Extracellular vesicles, tissue factor, cancer and thrombosis - discussion themes of the ISEV 2014 Educational Day.

Chris Gardiner, Paul Harrison, Mattias Belting, Anita Böing, Elena Campello, Bob S Carter, Mary E Collier, Frank Coumans, Camille Ettelaie, Nick van Es and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of extracellular vesicles, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. The pathogenesis of cancer-associated thrombosis.International journal of hematology · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Cancer-associated venous thromboembolism.Nature reviews. Disease primers · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Chris GardinerNuffield Department of Obstetrics and Gynaecology, University of Oxford, Level 3 Women's Centre, John Radcliffe Hospital, Oxford, UK; chris.gardiner@obs-gyn.ox.ac.uk.
Paul HarrisonSchool of Immunity and Infection, University of Birmingham Medical School, Birmingham, UK.
Mattias BeltingDepartment of Oncology and Pathology, Clinical Sciences, Skåne University Hospital, Lund, Sweden.
Anita BöingDepartment of Clinical Chemistry, Academic Medical Centre of the University of Amsterdam, Amsterdam, The Netherlands.
Elena CampelloDepartment of Cardiologic, Thoracic and Vascular Sciences, University of Padua Medical School, Padua, Italy.
Bob S CarterDivision of Neurosurgery, University of California San Diego, La Jolla, CA, USA.
Mary E CollierDepartment of Cardiovascular Sciences, University of Leicester, Clinical Sciences Wing, Glenfield General Hospital, Leicester, UK.
Frank CoumansDepartment of Clinical Chemistry, Academic Medical Centre of the University of Amsterdam, Amsterdam, The Netherlands.
Camille EttelaieSchool of Biological, Biomedical and Environmental Sciences, The University of Hull, Hull, UK.
Nick van EsDepartment of Vascular Medicine, Academic Medical Centre of the University of Amsterdam, Amsterdam, The Netherlands.
Fred H HochbergDivision of Neurosurgery, University of California San Diego, La Jolla, CA, USA.
Nigel MackmanThrombosis and Hemostasis Program, Department of Medicine, UNC McAllister Heart Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Robert C RennertDivision of Neurosurgery, University of California San Diego, La Jolla, CA, USA.
Johannes ThalerClinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
Janusz RakDepartment of Pediatrics, McGill University, Montreal Children's Hospital Research Institute MUHC, Montreal, QC, Canada.
Rienk NieuwlandDepartment of Clinical Chemistry, Academic Medical Centre of the University of Amsterdam, Amsterdam, The Netherlands.

Funding

exRNA Biomarkers for Human GliomaUH3TR000931 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CARTER, BOB S, HOCHBERG, FRED H · 2015 to 2017
$3.0M
exRNA Biomarkers for Human GliomaUH2TR000931 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CARTER, BOB S, HOCHBERG, FRED H · 2013 to 2014
$1.1M
Medical Research Council MR/J003360/1NCATS NIH HHS UH2 TR000931NCATS NIH HHS UH3 TR000931
6 · The paper itself

Abstract

Although the association between cancer and venous thromboembolism (VTE) has long been known, the mechanisms are poorly understood. Circulating tissue factor-bearing extracellular vesicles have been proposed as a possible explanation for the increased risk of VTE observed in some types of cancer. The International Society for Extracellular Vesicles (ISEV) and International Society on Thrombosis and Haemostasis (ISTH) held a joint Educational Day in April 2014 to discuss the latest developments in this field. This review discusses the themes of that event and the ISEV 2014 meeting that followed.

Indexed as

cancerextracellular vesiclesthrombosistissue factor

Identifiers

PMID25773446
PMCPMC4359985

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.