ArticleCell reports2015
The N-Terminal Domain of SIRT1 Is a Positive Regulator of Endogenous SIRT1-Dependent Deacetylation and Transcriptional Outputs.
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Article in Cell reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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46citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
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Who cites it
46 citing papers in PubMed, 76 citations in OpenAlex.
- Oridonin Protects Mice Against Cadmium-induced Kidney Injury by Inhibiting Ferroptosis via SIRT1 Regulation.Biological trace element research · 2026Article
- The Effects of Phosphorylation on the Structure and Function of Motif A, an Intrinsically Disordered Region within SIRT1.Biochemistry · 2026Article
- SIRT1 Exon 2-Encoded IDR Gates CREB-Dependent Transcriptional Timing During Fasting.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Factors Determining Sirtuin-1 Target Engagement.Advanced biology · 2026Review
- Mechanistic basis of N-terminal domain-mediated allostery in SIRT6: integrating molecular dynamics simulations and biochemical assays.Molecular diversity · 2026Article
- The Effects of Phosphorylation on the Structure and Function of Motif A, an Intrinsically Disordered Region within SIRT1.bioRxiv : the preprint server for biology · 2026Article
- Renoprotective effect of diosmin against chlorpyrifos-induced kidney injury is mediated by the regulation of TLR4/HMGB1/NF-κB, PPAR-γ/SIRT1, and Bax/Bcl2 signals.Journal of molecular histology · 2025Article
- Article
- Review
- NCAPD3 promotes diffuse large B-cell lymphoma progression through modulating SIRT1 expression in an H3K9 monomethylation-dependent manner.Journal of advanced research · 2025Article
- Decoding NAD+ Metabolism in COVID-19: Implications for Immune Modulation and Therapy.Vaccines · 2024Review
- Sirtuin 1 regulates the phenotype and functions of dendritic cells through Ido1 pathway in obesity.Cell death & disease · 2024Article
- Inhibitory protein-protein interactions of the SIRT1 deacetylase are choreographed by post-translational modification.Protein science : a publication of the Protein Society · 2024Article
- Article
- MiR-196b-3p and miR-450b-3p are key regulators of adipogenesis in porcine intramuscular and subcutaneous adipocytes.BMC genomics · 2023Article
- The deacetylation of Akt by SIRT1 inhibits inflammation in macrophages and protects against sepsis.Experimental biology and medicine (Maywood, N.J.) · 2023Article
- The differing effects of a dual acting regulator on SIRT1.Frontiers in molecular biosciences · 2023Article
- Sex and gender differences in myocarditis and dilated cardiomyopathy: An update.Frontiers in cardiovascular medicine · 2023Review
- O-GlcNAcylation of SIRT1 Protects against Cold Stress-Induced Skeletal Muscle Damage via Amelioration of Mitochondrial Homeostasis.International journal of molecular sciences · 2022Article
- Prediction and confirmation of a switch-like region within the N-terminal domain of hSIRT1.Biochemistry and biophysics reports · 2022Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Fiorella GhisaysDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, Saint Louis, MO 63110, USA.
Cynthia S BraceDepartment of Developmental Biology, Washington University School of Medicine, Saint Louis, MO 63110, USA.
Shawn M YacklyDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, Saint Louis, MO 63110, USA.
Hyock Joo KwonDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, Saint Louis, MO 63110, USA.
Kathryn F MillsDepartment of Developmental Biology, Washington University School of Medicine, Saint Louis, MO 63110, USA.
Elena KashentsevaDepartment of Radiation Oncology, Washington University School of Medicine, Saint Louis, MO 63110, USA.
Igor P DmitrievDepartment of Radiation Oncology, Washington University School of Medicine, Saint Louis, MO 63110, USA.
David T CurielDepartment of Radiation Oncology, Washington University School of Medicine, Saint Louis, MO 63110, USA.
Shin-Ichiro ImaiDepartment of Developmental Biology, Washington University School of Medicine, Saint Louis, MO 63110, USA. Electronic address: imaishin@wustl.edu.
Tom EllenbergerDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, Saint Louis, MO 63110, USA. Electronic address: tome@wustl.edu.
Washington University in St. Louis · US
Funding
WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Jennifer Lynn Powers Carson · 2013 to 2026
$27.1MSTRUCTURAL STUDIES OF DNA REPAIR PROTEINSR01GM052504 · NIGMS · WASHINGTON UNIVERSITY · PI ELLENBERGER, TOM E. · 1995 to 2011
$3.8MENAMPT-MEDIATED ADIPO-HYPOTHALAMIC COMMUNICATION FOR NAD+ PRODUCTION AND AGINGR01AG047902 · NIA · WASHINGTON UNIVERSITY · PI IMAI, SHIN-ICHIRO · 2014 to 2023
$3.2MTHE ROLE OF DORSOMEDIAL HYPOTHALAMIC NEURONS IN MAMMALIAN AGING AND LONGEVITYR01AG037457 · NIA · WASHINGTON UNIVERSITY · PI IMAI, SHIN-ICHIRO · 2011 to 2020
$3.1MMAMMALIAN SIR2 FUNCTION IN PANCREATIC BETA CELLSR01AG024150 · NIA · WASHINGTON UNIVERSITY · PI IMAI, SHIN-ICHIRO · 2004 to 2012
$2.7MTargeted-and Image-Based Adenovirus Cancer Therapeutic VectorsR01CA154697 · NCI · WASHINGTON UNIVERSITY · PI CURIEL, DAVID TERRY, MATHIS, J. MICHAEL · 2011 to 2015
$2.4MNCI NIH HHS R01 CA154697NIA NIH HHS R01 AG024150NIA NIH HHS R01 AG037457NIA NIH HHS R01 AG047902NIDDK NIH HHS P30 DK020579NIGMS NIH HHS R01 GM052504
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