Evidence map›Paper›PMID 25772248›Full record

ArticleAdvanced healthcare materials2015

Silk-based biomaterials in biomedical textiles and fiber-based implants.

Gang Li, Yi Li, Guoqiang Chen, Jihuan He, Yifan Han, Xiaoqin Wang, David L Kaplan

Open access · greenAbstract read
In one paragraph

Article in Advanced healthcare materials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 187 citations in OpenAlex.

  1. Engineering Silk Fibroin-Based Biomaterials for Neural Repair.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
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  3. Article
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  7. Article
  8. Review
  9. Review
  10. Biomimetic Scaffolds for Tendon Tissue Regeneration.Biomimetics (Basel, Switzerland) · 2023
    Review
  11. Review
  12. Review
  13. Review
  14. Design and computational optimization of compliance-matching aortic grafts.Frontiers in bioengineering and biotechnology · 2023
    Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Gang LiNational Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou, 215123, China.
Yi LiInstitute of Textiles and Clothing, The Hong Kong Polytechnic University, Hong Kong, China.
Guoqiang ChenNational Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou, 215123, China.
Jihuan HeNational Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou, 215123, China.
Yifan HanDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China.
Xiaoqin WangNational Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou, 215123, China.
David L KaplanDepartment of Biomedical Engineering, Tufts University, 4 Colby St, Room 153, Medford, MA, 02155, USA.
Soochow University · CNHong Kong Polytechnic University · HKTufts University · US

Funding

Translational Bioreactors - Engineering Complex TissuesP41EB002520 · NIBIB · TUFTS UNIVERSITY MEDFORD · PI KAPLAN, DAVID L. · 2004 to 2018
$16.7M
NIBIB NIH HHS P41 EB002520
6 · The paper itself

Abstract

Biomedical textiles and fiber-based implants (BTFIs) have been in routine clinical use to facilitate healing for nearly five decades. Amongst the variety of biomaterials used, silk-based biomaterials (SBBs) have been widely used clinically viz. sutures for centuries and are being increasingly recognized as a prospective material for biomedical textiles. The ease of processing, controllable degradability, remarkable mechanical properties and biocompatibility have prompted the use of SBBs for various BTFIs for extracorporeal implants, soft tissue repair, healthcare/hygiene products and related needs. The present Review focuses on BTFIs from the perspective of types and physical and biological properties, and this discussion is followed with an examination of the advantages and limitations of BTFIs from SBBs. The Review covers progress in surface coatings, physical and chemical modifications of SBBs for BTFIs and identifies future needs and opportunities for the further development for BTFIs using SBBs.

Indexed as

Prostheses and ImplantsAnimalsBiocompatible MaterialsBiomedical TechnologyBombyxChemical PhenomenaHumansMechanical PhenomenaSilkSpidersTissue EngineeringTissue ScaffoldsBiocompatible MaterialsSilkbiomedical textilesdevicesimplantsmedical applicationssilk-based biomaterialssurface modifications

Identifiers

PMID25772248
PMCPMC4456268
OpenAlexW2039580257

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.