Evidence map›Paper›PMID 25771993›Full record

ReviewAdvanced healthcare materials2015

Fabricated Elastin.

Giselle C Yeo, Behnaz Aghaei-Ghareh-Bolagh, Edwin P Brackenreg, Matti A Hiob, Pearl Lee, Anthony S Weiss

Erratum issuedAbstract readReview
In one paragraph

Review in Advanced healthcare materials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
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  5. Review
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  9. Article
  10. Article
  11. Materials today. Bio · 2022
    Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
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  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Giselle C YeoCharles Perkins Centre, The University of Sydney, NSW 2006, Australia.
Behnaz Aghaei-Ghareh-Bolagh *Charles Perkins Centre, The University of Sydney, NSW 2006, Australia.
Edwin P Brackenreg *Charles Perkins Centre, The University of Sydney, NSW 2006, Australia.
Matti A Hiob *Charles Perkins Centre, The University of Sydney, NSW 2006, Australia.
Pearl Lee *Charles Perkins Centre, The University of Sydney, NSW 2006, Australia.
Anthony S WeissCharles Perkins Centre, The University of Sydney, NSW 2006, Australia.

Funding

Multifunctional Tropoelastin-Silk Biomaterial SystemsR01EB014283 · NIBIB · TUFTS UNIVERSITY MEDFORD · PI KAPLAN, DAVID L. · 2012 to 2015
$1.2M
NIBIB NIH HHS R01 EB014283
6 · The paper itself

Abstract

The mechanical stability, elasticity, inherent bioactivity, and self-assembly properties of elastin make it a highly attractive candidate for the fabrication of versatile biomaterials. The ability to engineer specific peptide sequences derived from elastin allows the precise control of these physicochemical and organizational characteristics, and further broadens the diversity of elastin-based applications. Elastin and elastin-like peptides can also be modified or blended with other natural or synthetic moieties, including peptides, proteins, polysaccharides, and polymers, to augment existing capabilities or confer additional architectural and biofunctional features to compositionally pure materials. Elastin and elastin-based composites have been subjected to diverse fabrication processes, including heating, electrospinning, wet spinning, solvent casting, freeze-drying, and cross-linking, for the manufacture of particles, fibers, gels, tubes, sheets and films. The resulting materials can be tailored to possess specific strength, elasticity, morphology, topography, porosity, wettability, surface charge, and bioactivity. This extraordinary tunability of elastin-based constructs enables their use in a range of biomedical and tissue engineering applications such as targeted drug delivery, cell encapsulation, vascular repair, nerve regeneration, wound healing, and dermal, cartilage, bone, and dental replacement.

Indexed as

AnimalsBiocompatible MaterialsDrug Delivery SystemsElastinHumansPeptidesProtein EngineeringTissue ScaffoldsBiocompatible MaterialsElastinPeptidesbiomaterialselastinelastin-like peptidesfabricationtissue engineeringtropoelastin

Identifiers

PMID25771993
PMCPMC4568180

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.