Evidence map›Paper›PMID 25771535›Full record

SynthesisMedical science monitor : international medical journal of experimental and clinical research2015

Association between dietary cadmium exposure and breast cancer risk: an updated meta-analysis of observational studies.

Xiujuan Wu, Xiaofeng Zhu, Mingjun Xie

Open access · hybridAbstract readMeta-Analysis
In one paragraph

Synthesis in Medical science monitor : international medical journal of experimental and clinical research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Effects of lead and cadmium on the immune system and cancer progression.Journal of environmental health science & engineering · 2020
    Review
  4. Article
  5. Cadmium exposure and the risk of breast cancer in Chaoshan population of southeast China.Environmental science and pollution research international · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Xiujuan WuDepartment of General Surgery, Luzhou Medical College, Luzhou, Sichuan, China (mainland).
Xiaofeng ZhuDepartment of Hematology, Luzhou Medical College, Luzhou, Sichuan, China (mainland).
Mingjun XieDepartment of General Surgery, First People's Hospital of Yibin, Yibin, Sichuan, China (mainland).
First Affiliated Hospital of Sichuan Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiet is the primary way cadmium (Cd) enters the body in those without occupational exposure and who do not inhabit Cd-polluted regions. Findings on the relationship between dietary Cd exposure and breast cancer (BC) risk have been inconsistent; a meta-analysis has supported this association but 2 recent cohort studies showed inconsistent results. Hence, we performed an updated meta-analysis to re-evaluate the association between dietary Cd exposure and BC risk. MATERIAL AND

methodsWe searched PubMed, Medline, and EMBASE to identify relevant studies published through September 2014. Combined relative risks (RRs) and the corresponding 95% confidence intervals (CIs) were used to assess the association between dietary Cd exposure and BC risk.

resultsWe identified 6 studies involving 321 315 participants and 11 978 cases. Our study suggested there was no statistically significant positive association between dietary Cd exposure and BC risk, the combined RR and corresponding 95% CI was 1.01 [0.88, 1.14]. The result was not modified by menopause status, geographic area, or study design.

conclusionsOur study did not find a statistically significant positive association between dietary Cd exposure and BC risk. It is necessary to investigate this relationship among the high-risk groups and more cohort studies based on diverse populations are needed.

Indexed as

Observational Studies as TopicBreast NeoplasmsCadmiumDietFemaleHumansPublication BiasRisk FactorsCadmium

Identifiers

PMID25771535
PMCPMC4371715
OpenAlexW2086864609

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.