ArticleNeuroscience2015
Extrinsic origins of the somatostatin and neuropeptide Y innervation of the rat basolateral amygdala.
Article in Neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 21 citations in OpenAlex.
- Affective tactile stimulation ameliorates chronic pain and comorbid anxiety by modulating hippocampal CA1 oscillations and functional connectivity.Frontiers in molecular neuroscience · 2026Article
- Activation of NPY Receptors in the BLA Inhibits Projections to the Bed Nucleus of the Stria Terminalis and Buffers Stress-Induced Decreases in Social Interaction in Male Rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Functional neuroanatomy of basal forebrain projections to the basolateral amygdala: Transmitters, receptors, and neuronal subpopulations.Journal of neuroscience research · 2024Review
- The neurophysiological basis of stress and anxiety - comparing neuronal diversity in the bed nucleus of the stria terminalis (BNST) across species.Frontiers in cellular neuroscience · 2023Review
- Gastrin-releasing peptide regulates fear learning under stressed conditions via activation of the amygdalostriatal transition area.Molecular psychiatry · 2022Article
- Recent advances in neuropeptide-related omics and gene editing: Spotlight on NPY and somatostatin and their roles in growth and food intake of fish.Frontiers in endocrinology · 2022Review
- Amygdala-hippocampal interactions in synaptic plasticity and memory formation.Neurobiology of learning and memory · 2021Review
- Diversity and function of corticopetal and corticofugal GABAergic projection neurons.Nature reviews. Neuroscience · 2020Review
- Contribution of NPY YThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Functional neuroanatomy of the basolateral amygdala: Neurons, neurotransmitters, and circuits.Handbook of behavioral neuroscience · 2020Article
- Neuronal diversity of the amygdala and the bed nucleus of the stria terminalis.Handbook of behavioral neuroscience · 2020Article
- Functional neuroanatomy of amygdalohippocampal interconnections and their role in learning and memory.Journal of neuroscience research · 2017Review
- Structure and function of the amygdaloid NPY system: NPY Y2 receptors regulate excitatory and inhibitory synaptic transmission in the centromedial amygdala.Brain structure & function · 2016Article
- Neuropeptide Y input to the rat basolateral amygdala complex and modulation by conditioned fear.The Journal of comparative neurology · 2016Article
- Localization of the M2 muscarinic cholinergic receptor in dendrites, cholinergic terminals, and noncholinergic terminals in the rat basolateral amygdala: An ultrastructural analysis.The Journal of comparative neurology · 2016Article
- Mu opioid receptor localization in the basolateral amygdala: An ultrastructural analysis.Neuroscience · 2015Article
- Corticofugal GABAergic projection neurons in the mouse frontal cortex.Frontiers in neuroanatomy · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The amygdalar basolateral nuclear complex (BLC) is a cortex-like structure that receives inputs from many cortical areas. It has long been assumed that cortico-amygdalar projections, as well as inter-areal intracortical connections, arise from cortical pyramidal cells. However, recent studies have shown that GABAergic long-range nonpyramidal neurons (LRNP neurons) in the cortex also contribute to inter-areal connections. The present study combined Fluorogold (FG) retrograde tract tracing with immunohistochemistry for cortical nonpyramidal neuronal markers to determine if cortical LRNP neurons project to the BLC in the rat. Injections of FG into the BLC produced widespread retrograde labeling in the cerebral hemispheres and diencephalon. Triple-labeling for FG, somatostatin (SOM), and neuropeptide Y (NPY) revealed a small number of FG+/SOM+/NPY+ neurons and FG+/SOM+/NPY- neurons in the lateral entorhinal area, amygdalopiriform transition area, and piriform cortex, but not in the prefrontal and insular cortices, or in the diencephalon. In addition, FG+/SOM+/NPY+ neurons were observed in the amygdalostriatal transition area and in a zone surrounding the intercalated nuclei. About half of the SOM+ neurons in the lateral entorhinal area labeled by FG were GABA+. FG+ neurons containing parvalbumin were only seen in the basal forebrain, and no FG+ neurons containing vasoactive intestinal peptide were observed in any brain region. Since LRNP neurons involved in corticocortical connections are critical for synchronous oscillations that allow temporal coordination between distant cortical regions, the LRNP neurons identified in this study may play a role in the synchronous oscillations of the BLC and hippocampal region that are involved in the retrieval of fear memories.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.