ReviewChinese journal of natural medicines2015
Cycloartenol triterpenoid saponins from Cimicifuga simplex (Ranunculaceae) and their biological effects.
Review in Chinese journal of natural medicines, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 18 citations in OpenAlex.
- GC-MS analysis, comprehensive biological profiling, molecular docking and ADMET studies ofFuture science OA · 2025Article
- Anti-Inflammatory and Antioxidant Activities of Lipophilic Fraction fromInternational journal of molecular sciences · 2023Article
- Phytochemical Composition and Detection of Novel Bioactives in Anther Callus ofPlants (Basel, Switzerland) · 2023Article
- Fibrous Roots of Cimicifuga Are at Risk of Hepatotoxicity.Molecules (Basel, Switzerland) · 2022Article
- Aqueous Extract ofJournal of inflammation research · 2022Article
- Antiacetylcholinesterase triterpenes from the fruits ofRSC advances · 2018Article
- Immunomodulatory Effect of Agave tequilana Evaluated on an Autoimmunity Like-SLE Model Induced in Balb/c Mice with Pristane.Molecules (Basel, Switzerland) · 2017Article
- Exploring the Efficacy and Safety of Black Cohosh (Journal of mid-life healthReview
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The constituents of Cimicifuga plants have been extensively investigated, and the principal metabolites are 9,19-cyclolanostane triterpenoid glycosides, which are distributed widely in Cimicifuga plants, but not in other members of the Ranunculaceae family, and are considered to be characteristics of the Cimicifuga genus. This type of triterpenoid glycoside possesses several important biological activities. More than 120 cycloartane triterpene glycosides have been isolated from Cimicifuga simplex Wormsk. The aim of this review article is to summarize all the major findings based on the available scientific literatures on C. simplex, with a focus on the identified 9,19-cyclolanostane triterpenoid glycosides. Biological studies of cycloartane triterpene glycosides from Cimicifuga spp. are also discussed.
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