ArticleApplied and environmental microbiology2015
Taxonomic Identification of Ruminal Epithelial Bacterial Diversity during Rumen Development in Goats.
Article in Applied and environmental microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
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Who cites it
60 citing papers in PubMed.
- Bidirectional regulation of gut microbiota and young ruminant host: implications for intestinal development and mucosal immunity.Journal of animal science and biotechnology · 2026Review
- Rumen microbiota and fermentation parameters in Tibetan semi-fine wool sheep reflect growth stages and potential nutritional adaptations.Animal bioscience · 2026Article
- Multiomics insights into rumen microbiome and function in grazing lambs: implications for nutrient absorption and grassland sustainability.Microbiome · 2025Article
- Effects of dietary supplementation with Bacillus coagulans on growth and immune performance, rumen microorganisms, and metabolites of yaks.BMC microbiology · 2025Article
- Dietary selection of distinct gastrointestinal microorganisms drives fiber utilization dynamics in goats.Microbiome · 2025Article
- Effects of different fiber levels of energy feeds on rumen fermentation and the microbial community structure of grazing sheep.BMC microbiology · 2025Article
- Enhancing nutrient efficiency through optimizing protein levels in lambs: Involvement of gastrointestinal microbiota.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- No rumen fermentation profiles and associated microbial diversities difference were found between Hu sheep and Karakul sheep fed a cottonseed hull diet.Microbiome · 2025Article
- Discrepancies in the rumen microbiome, metabolome, and serum metabolome among Hu sheep, East Friesian sheep, and East Friesian × Hu crossbred sheep.Frontiers in microbiology · 2025Article
- Recent nutritional strategies and feed additives to stimulate proper rumen development in young goats.Translational animal science · 2025Article
- Dataset of the rumen microbiota and epithelial transcriptomics and proteomics in goat affected by solid diets.Scientific data · 2024Article
- Microbiota and Metabolite Profiles in the Feces of Juvenile Sika Deer (Animals : an open access journal from MDPI · 2024Article
- Multi-omics analysis reveals the effects of host-rumen microbiota interactions on growth performance in a goat model.Frontiers in microbiology · 2024Article
- Single-cell transcriptome and metagenome profiling reveals the genetic basis of rumen functions and convergent developmental patterns in ruminants.Genome research · 2023Article
- Physical, Metabolic, and Microbial Rumen Development in Goat Kids: A Review on the Challenges and Strategies of Early Weaning.Animals : an open access journal from MDPI · 2023Review
- The Colonization of Rumen Microbiota and Intervention in Pre-Weaned Ruminants.Animals : an open access journal from MDPI · 2023Review
- The epithelial transcriptome and mucosal microbiota are altered for goats fed with a low-protein diet.Frontiers in microbiology · 2023Article
- Age- and Microbiota-Dependent Cell Stemness Plasticity Revealed by Cattle Cell Landscape.Research (Washington, D.C.) · 2023Article
- Microbiota-host crosstalk in the newborn and adult rumen at single-cell resolution.BMC biology · 2022Article
- Understanding the role of rumen epithelial host-microbe interactions in cattle feed efficiency.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2022Review
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4 authors.
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Abstract
Understanding of the colonization process of epithelial bacteria attached to the rumen tissue during rumen development is very limited. Ruminal epithelial bacterial colonization is of great significance for the relationship between the microbiota and the host and can influence the early development and health of the host. MiSeq sequencing of 16S rRNA genes and quantitative real-time PCR (qPCR) were applied to characterize ruminal epithelial bacterial diversity during rumen development in this study. Seventeen goat kids were selected to reflect the no-rumination (0 and 7 days), transition (28 and 42 days), and rumination (70 days) phases of animal development. Alpha diversity indices (operational taxonomic unit [OTU] numbers, Chao estimate, and Shannon index) increased (P < 0.01) with age, and principal coordinate analysis (PCoA) revealed that the samples clustered together according to age group. Phylogenetic analysis revealed that Proteobacteria, Firmicutes, and Bacteroidetes were detected as the dominant phyla regardless of the age group, and the abundance of Proteobacteria declined quadratically with age (P < 0.001), while the abundances of Bacteroidetes (P = 0.088) and Firmicutes (P = 0.009) increased with age. At the genus level, Escherichia (80.79%) dominated at day zero, while Prevotella, Butyrivibrio, and Campylobacter surged (linearly; P < 0.01) in abundance at 42 and 70 days. qPCR showed that the total copy number of epithelial bacteria increased linearly (P = 0.013) with age. In addition, the abundances of the genera Butyrivibrio, Campylobacter, and Desulfobulbus were positively correlated with rumen weight, rumen papilla length, ruminal ammonia and total volatile fatty acid concentrations, and activities of carboxymethylcellulase (CMCase) and xylanase. Taking the data together, colonization by ruminal epithelial bacteria is age related (achieved at 2 months) and might participate in the anatomic and functional development of the rumen.
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