Evidence map›Paper›PMID 25768868›Full record

SynthesisJournal of acquired immune deficiency syndromes (1999)2015

Integrating prevention interventions for people living with HIV into care and treatment programs: a systematic review of the evidence.

Amy Medley, Pamela Bachanas, Michael Grillo, Nina Hasen, Ugochukwu Amanyeiwe

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of acquired immune deficiency syndromes (1999), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 6 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 6 syntheses or guidelines pooled it, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Amy Medley*US Centers for Disease Control and Prevention, Division of Global HIV/AIDS, Atlanta, GA; †Naval Health Research Center, Department of Defense, HIV/AIDS Prevention Program, San Diego, CA; ‡U.S. Department of State, Office of the US Global AIDS Coordinator and Health Diplomacy, Washington, DC; and §US Agency for International Development, Office of HIV/AIDS, Washington, DC.
Pamela Bachanas
Michael Grillo
Nina Hasen
Ugochukwu Amanyeiwe
Centers for Disease Control and Prevention · USNaval Health Research Center · USUnited States Department of State · US

Funding

Intramural CDC HHS CC999999PEPFAR
6 · The paper itself

Abstract

introductionThis review assesses the impact of prevention interventions for people living with HIV on HIV-related mortality, morbidity, retention in care, quality of life, and prevention of ongoing HIV transmission in resource-limited settings (RLSs).

methodsWe conducted a systematic review of studies reporting the results of prevention interventions for people living with HIV in RLS published between January 2000 and August 2014. Standardized methods of searching and data abstraction were used.

resultsNinety-two studies met the eligibility criteria: 24 articles related to adherence counseling and support, 13 on risk reduction education and condom provision, 19 on partner HIV testing and counseling, 14 on provision of family planning services, and 22 on assessment and treatment of other sexually transmitted infections. Findings indicate good evidence that adherence counseling and sexually transmitted infection treatment can have a high impact on morbidity, whereas risk reduction education, partner HIV testing and counseling, and family planning counseling can prevent transmission of HIV. More limited evidence was found to support the impact of these interventions on retention in care and quality of life. Most studies did not report cost information, making it difficult to draw conclusions about the cost-effectiveness of these interventions.

conclusionsThis evidence suggests that these prevention interventions, if brought to sufficient scale and coverage, can help support and optimize the impact of core treatment and prevention interventions in RLS. Further operational research with more rigorous study designs, and ideally with biomarkers and costing information, is needed to determine the best model for providing these interventions in RLS.

Indexed as

AdultCost-Benefit AnalysisCounselingDeveloping CountriesHealth Impact AssessmentHealth ResourcesHIV InfectionsHumansOutcome Assessment, Health CareQuality of LifeRisk Reduction BehaviorSex EducationSexual Partners

Identifiers

PMID25768868
PMCPMC4666299
OpenAlexW2012451139

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.