ReviewInternational journal of molecular sciences2015
Mechanisms by which different functional states of mitochondria define yeast longevity.
Review in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Article
- Metabolomic Profiling ofJournal of fungi (Basel, Switzerland) · 2026Article
- Tra1 controls the transcriptional landscape of the aging cell.G3 (Bethesda, Md.) · 2023Article
- Caloric restriction causes a distinct reorganization of the lipidome in quiescent and non-quiescent cells of budding yeast.Oncotarget · 2021Article
- Article
- Mechanisms that Link Chronological Aging to Cellular Quiescence in Budding Yeast.International journal of molecular sciences · 2020Review
- Article
- Mechanisms by which PE21, an extract from the white willowOncotarget · 2019Article
- Mechanisms Through Which Some Mitochondria-Generated Metabolites Act as Second Messengers That Are Essential Contributors to the Aging Process in Eukaryotes Across Phyla.Frontiers in physiology · 2019Review
- Mitochondria reorganization upon proliferation arrest predicts individual yeast cell fate.eLife · 2018Article
- Mechanisms through which lithocholic acid delays yeast chronological aging under caloric restriction conditions.Oncotarget · 2018Article
- Yeast Cells Exposed to Exogenous Palmitoleic Acid Either Adapt to Stress and Survive or Commit to Regulated Liponecrosis and Die.Oxidative medicine and cellular longevity · 2018Review
- Comparative Study for the Association of Mitochondrial Haplogroup F+ and Metabolic Syndrome between Longevity and Control Population in Guangxi Zhuang Autonomous Region, China.The journal of nutrition, health & aging · 2018Article
- Yeast quiescence exit swiftness is influenced by cell volume and chronological age.Microbial cell (Graz, Austria) · 2017Article
- Article
- Inactivation of RAD52 and HDF1 DNA repair genes leads to premature chronological aging and cellular instability.Journal of biosciences · 2017Article
- Article
- Mechanisms Underlying the Essential Role of Mitochondrial Membrane Lipids in Yeast Chronological Aging.Oxidative medicine and cellular longevity · 2017Review
- Discovery of plant extracts that greatly delay yeast chronological aging and have different effects on longevity-defining cellular processes.Oncotarget · 2016Article
- A novel approach to the discovery of anti-tumor pharmaceuticals: searching for activators of liponecrosis.Oncotarget · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Mitochondrial functionality is vital to organismal physiology. A body of evidence supports the notion that an age-related progressive decline in mitochondrial function is a hallmark of cellular and organismal aging in evolutionarily distant eukaryotes. Studies of the baker's yeast Saccharomyces cerevisiae, a unicellular eukaryote, have led to discoveries of genes, signaling pathways and chemical compounds that modulate longevity-defining cellular processes in eukaryotic organisms across phyla. These studies have provided deep insights into mechanistic links that exist between different traits of mitochondrial functionality and cellular aging. The molecular mechanisms underlying the essential role of mitochondria as signaling organelles in yeast aging have begun to emerge. In this review, we discuss recent progress in understanding mechanisms by which different functional states of mitochondria define yeast longevity, outline the most important unanswered questions and suggest directions for future research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.