ArticleBiochemistry research international2015
Phytochemical Analysis and Biological Activities of Cola nitida Bark.
Article in Biochemistry research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Therapeutic potential ofFrontiers in behavioral neuroscience · 2026Article
- Entomotherapy as an alternative treatment for diseases due to Gram-negative bacteria in Burkina Faso.Scientific reports · 2024Article
- Antioxidant, Anti-Inflammatory, and Anti-Cancer Properties of Amygdalin Extracted from Three Cassava Varieties Cultivated in Benin.Molecules (Basel, Switzerland) · 2023Article
- Mung Bean (Plants (Basel, Switzerland) · 2022Article
- Indigenous Nigeria medicinal herbal remedies: A potential source for therapeutic against rheumatoid arthritis.Experimental biology and medicine (Maywood, N.J.) · 2022Review
- Anti-Inflammatory and Anti-Colon Cancer Activities of Mung Bean Grown in Burkina Faso.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Phytochemical composition andSaudi journal of biological sciences · 2021Article
- Formulation and In Vitro Evaluation of Oral Capsules and Suspension from the Ethanolic Extract ofBioMed research international · 2021Article
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Authors and funding
11 authors.
Funding
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Abstract
Kola nut is chewed in many West African cultures and is used ceremonially. The aim of this study is to investigate some biological effects of Cola nitida's bark after phytochemical screening. The bark was collected, dried, and then powdered for the phytochemical screening and extractions. Ethanol and ethyl acetate extracts of C. nitida were used in this study. The antibacterial activity was tested on ten reference strains and 28 meat isolated Staphylococcus strains by disc diffusion method. The antifungal activity of three fungal strains was determined on the Potato-Dextrose Agar medium mixed with the appropriate extract. The antioxidant activity was determined by DPPH and ABTS methods. Our data revealed the presence of various potent phytochemicals. For the reference and meat isolated strains, the inhibitory diameter zone was from 17.5 ± 0.7 mm (C. albicans) to 9.5 ± 0.7 mm (P. vulgaris). The MIC ranged from 0.312 mg/mL to 5.000 mg/mL and the MBC from 0.625 mg/mL to >20 mg/mL. The highest antifungal activity was observed with F. verticillioides and the lowest one with P. citrinum. The two extracts have an excellent reducing free radical activity. The killing effect of A. salina larvae was perceptible at 1.04 mg/mL. The purified extracts of Cola nitida's bark can be used to hold meat products and also like phytomedicine.
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