Evidence map›Paper›PMID 25767633›Full record

ArticleThe open AIDS journal2015

LETTER TO THE EDITOR Performance of the ViroSeq® HIV-1 Genotyping System v2.0 in Central Africa.

Linda Chapdeleine Mekue Mouafo, Hélène Péré, Angélique Ndjoyi-Mbiguino, Donato Koyalta, Jean De Dieu Longo, François-Xavier Mbopi-Kéou, Coumba Toure Kane, Laurent Bélec

Abstract readLetter
In one paragraph

Article in The open AIDS journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Nucleic acid testing and molecular characterization of HIV infections.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019
    Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Linda Chapdeleine Mekue MouafoUniversity of Dschang, Dschang, Cameroon ; Assistance Publique - Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.
Hélène PéréAssistance Publique - Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France ; Faculté de Médecine Paris Descartes, Université Paris Descartes (Paris V), Sorbonne Paris Cité, Paris, France.
Angélique Ndjoyi-MbiguinoUniversité des Sciences de la Santé, Libreville, Gabon.
Donato KoyaltaMinistère de la Santé Publique, N'Djamena, Chad.
Jean De Dieu LongoCentre National de Référence des Maladies Sexuellement Transmissibles, et de la Thérapie Antirétrovirale, and Unité de Recherches et d'Intervention sur les Maladies Sexuellement Transmissibles et le SIDA, Département de Santé Publique, Faculté des Sciences de la Santé de Bangui, Bangui, Central African Republic.
François-Xavier Mbopi-KéouLaboratoire National de Santé Hygiène Mobile, Ministry of Public Health, and Université de Yaoundé I, Yaoundé, Cameroon.
Coumba Toure KaneLaboratoire de Bactériologie-virologie, CHU Aristide Le Dantec, Dakar, Senegal.
Laurent BélecAssistance Publique - Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France ; Faculté de Médecine Paris Descartes, Université Paris Descartes (Paris V), Sorbonne Paris Cité, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resistance genotypes in pol gene of HIV-1 were obtained by the ViroSeq(®) HIV-1 Genotyping System v2.0 (Celera Diagnostics, Alameda, CA, USA) in 138 of 145 (95%) antiretroviral treatment-experienced adults in virological failure living in Central Africa (Cameroon, Central African Republic, Chad, Gabon). HIV-1 group M exhibited broad genetic diversity. Performance of the 7 ViroSeq(®) sequencing primers showed high failure rate, from 3% to 76% (D: 76%; F: 17%; A and H: 15%; G and B: 4%; C: 3%). These findings emphasize the need of updating the ViroSeq(®) HIV-1 genotyping system for non-B subtypes HIV-1.

Indexed as

Central Africanon-B subtypes HIV-1VirosSeq®HIV-1 Genotyping System v2.0

Identifiers

PMID25767633
PMCPMC4353127

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.