ArticleJournal of basic and clinical pharmacy2015
High acid phosphatase level in the gingival tissues of periodontitis subjects.
Article in Journal of basic and clinical pharmacy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Salivary microbiota dysbiosis and elevated polyamine levels contribute to the severity of periodontal disease.BMC oral health · 2025Article
- Article
- Probing the toxic mechanism of bisphenol A with acid phosphatase at the molecular level.Environmental science and pollution research international · 2018Article
- Correlations between gingival crevicular blood glucose and capillary blood glucose: A preliminary report.Journal of laboratory physiciansArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimPeriodontitis is one of the major problems slowly progressing and could affect 70% of the global population. The prevalence of periodontitis differs from mild to moderate forms of race and geographic region. The aim of this study is to determine the acid phosphatase (ACP) activity in the gingival tissues of periodontitis subjects. In this study, the activity of ACP in the gingival tissue of subjects with periodontitis was examined. MATERIALS AND
methodsA total of 30 subjects were selected for the study and are divided into group I (n = 15, healthy subjects in control) and in group II (n = 15, periodontitis subjects). The gingival tissue from group I and group II subjects were collected after the surgery and the ACP enzyme level was analyzed using ultraviolet spectrophotometer. Assessment of periodontitis was done based on periodontal probing depth (PPD) and clinical attachment level (CAL). The statistical analysis applied was independent sample t-test, P < 0.05 was considered as significant.
resultsThe results of group II periodontitis subjects showed statistically significant increased gingival tissues ACP level when compared with the control group I subject. The mean levels of CAL and PPD were significantly >4 mm in periodontitis subjects when compared to control.
conclusionsThe elevated level of ACP in the gingival tissue and Gram-negative microorganisms found in sub-gingival plaque was greater in periodontitis. Based on these results, gingival tissue ACP level can be considered as an independent risk factor for evaluating the microbial status and periodontal tissue damage.
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