ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2015
Ketamine: promising path or false prophecy in the development of novel therapeutics for mood disorders?
Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05008939 (Subanesthetic Sevoflurane for Treatment-Resistant Depression), which is not on this map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Subanesthetic Sevoflurane for Treatment-Resistant Depression: A Proof-of-Concept Trial
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Brain Changes Associated With Long-Term Ketamine Abuse, A Systematic Review.Frontiers in neuroanatomy · 2022Pooled it
- Potential antidepressant effect of amantadine: a review of preclinical studies and clinical trials.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)Pooled it
- Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism.The American journal of psychiatry · 2018Trial
- Current progress in targeted pharmacotherapy to treat symptoms of major depressive disorder: moving from broad-spectrum treatments to precision psychiatry.CNS spectrums · 2025Review
- A novel framework for ketamine-assisted couple therapy.Frontiers in psychiatry · 2024Review
- Ketamine: The final frontier or another depressing end?Behavioural brain research · 2020Review
- A Proof-of-Mechanism Study to Test Effects of the NMDA Receptor Antagonist Lanicemine on Behavioral Sensitization in Individuals With Symptoms of PTSD.Frontiers in psychiatry · 2019Article
- The Effect of Glutamatergic Modulators on Extracellular Glutamate: How Does this Information Contribute to the Discovery of Novel Antidepressants?Current therapeutic research, clinical and experimental · 2019Review
- Ketamine and rapid-acting antidepressants: a new era in the battle against depression and suicide.F1000Research · 2018Review
- Experimental medication treatment approaches for depression.Translational psychiatry · 2017Review
- Ketamine and Beyond: Investigations into the Potential of Glutamatergic Agents to Treat Depression.Drugs · 2017Review
- Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants.Nature medicine · 2016Article
- The positive effect on ketamine as a priming adjuvant in antidepressant treatment.Translational psychiatry · 2015Article
- Circumspectives: the promise of ketamine.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2015Article
- Antidepressant mechanism of ketamine: perspective from preclinical studies.Frontiers in neuroscience · 2015Review
Corrections and comments
- Erratum for
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.