ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2015
All APAPs Are Not Equivalent for the Treatment of Sleep Disordered Breathing: A Bench Evaluation of Eleven Commercially Available Devices.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Treatment of Adult Obstructive Sleep Apnea With Positive Airway Pressure: An American Academy of Sleep Medicine Systematic Review, Meta-Analysis, and GRADE Assessment.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019Pooled it
- Predicting optimal CPAP pressure in obstructive sleep apnea among Chinese patients using respiratory endotype derived from polysomnography.Scientific reports · 2026Article
- Evaluation of apap parameters in one to three nights titration for final pressure decision-making in a real world clinical setting.Sleep & breathing = Schlaf & Atmung · 2026Article
- Continuous positive airway pressure on left ventricular ejection fraction in obstructive sleep apnea and heart failure with reduced ejection fraction: a systematic review and meta-analysis.Sleep and biological rhythms · 2026Article
- Bench evaluation of six non-invasive ventilation home ventilators: comparison with an ICU ventilator and unsupervised clustering.BMJ open respiratory research · 2025Article
- Auto-adjusting positive airway pressure: the fine line between engineering and medicine.Sleep & breathing = Schlaf & Atmung · 2025Review
- Formulas to predict continuous positive airway pressure level using a home auto-adjusting device for obstructive sleep apnea treatment.Sleep & breathing = Schlaf & Atmung · 2024Article
- Accuracy of continuous positive airway pressure devices: the devil is in the details, the best is yet to come.Sleep & breathing = Schlaf & Atmung · 2023Article
- Impact of Unintentional Air Leaks on Automatic Positive Airway Pressure Device Performance in Simulated Sleep Apnea Events.Respiratory care · 2023Article
- Patients with Epiglottic Collapse Are Less Adherent to Autotitrating Positive Airway Pressure Therapy for Obstructive Sleep Apnea.Annals of the American Thoracic Society · 2022Article
- Impact of additional HEPA filter on APAP performance and CPAP pressure level in simulated sleep apnea events.Frontiers in medical technology · 2022Article
- Extended evaluation of the efficacy of a proactive forced oscillation technique-based auto-CPAP algorithm.Sleep & breathing = Schlaf & Atmung · 2020Article
- Use of the WatchPAT to detect occult residual sleep-disordered breathing in patients on CPAP for obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020Article
- Sudden Improvement in PAP Download Indices Without Treatment Change.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019Article
- Impact of Mask Type on the Effectiveness of and Adherence to Unattended Home-Based CPAP Titration.Sleep disorders · 2019Article
- New physiological bench test reproducing nocturnal breathing pattern of patients with sleep disordered breathing.PloS one · 2019Article
- Combined effects of leaks, respiratory system properties and upper airway patency on the performance of home ventilators: a bench study.BMC pulmonary medicine · 2017Article
- Pressure-Relief Features of Fixed and Autotitrating Continuous Positive Airway Pressure May Impair Their Efficacy: Evaluation with a Respiratory Bench Model.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2016Article
- Technology for noninvasive mechanical ventilation: looking into the black box.ERJ open research · 2016Review
- Treatment of sleep-disordered breathing with positive airway pressure devices: technology update.Medical devices (Auckland, N.Z.) · 2015Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesThis study challenged on a bench-test the efficacy of auto-titrating positive airway pressure (APAP) devices for obstructive sleep disordered breathing treatment and evaluated the accuracy of the device reports.
methodsOur bench consisted of an active lung simulator and a Starling resistor. Eleven commercially available APAP devices were evaluated on their reactions to single-type SDB sequences (obstructive apnea and hypopnea, central apnea, and snoring), and to a long general breathing scenario (5.75 h) simulating various SDB during four sleep cycles and to a short scenario (95 min) simulating one sleep cycle.
resultsIn the single-type sequence of 30-minute repetitive obstructive apneas, only 5 devices normalized the airflow (> 70% of baseline breathing amplitude). Similarly, normalized breathing was recorded with 8 devices only for a 20-min obstructive hypopnea sequence. Five devices increased the pressure in response to snoring. Only 4 devices maintained a constant minimum pressure when subjected to repeated central apneas with an open upper airway. In the long general breathing scenario, the pressure responses and the treatment efficacy differed among devices: only 5 devices obtained a residual obstructive AHI < 5/h. During the short general breathing scenario, only 2 devices reached the same treatment efficacy (p < 0.001), and 3 devices underestimated the AHI by > 10% (p < 0.001). The long scenario led to more consistent device reports.
conclusionLarge differences between APAP devices in the treatment efficacy and the accuracy of report were evidenced in the current study.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.