Evidence map›Paper›PMID 25765886›Full record

ArticleMathematical biosciences2015

Mathematical modeling of renal hemodynamics in physiology and pathophysiology.

Ioannis Sgouralis, Anita T Layton

Abstract read
In one paragraph

Article in Mathematical biosciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Renal blood flow and oxygenation.Pflugers Archiv : European journal of physiology · 2022
    Review
  12. Article
  13. Modeling the Steady-State Effects of Mean Arterial Pressure on the Kidneys.IEEE open journal of engineering in medicine and biology · 2021
    Article
  14. Article
  15. Sweet success? SGLT2 inhibitors and diabetes.American journal of physiology. Renal physiology · 2018
    Article
  16. Renal medullary and urinary oxygen tension during cardiopulmonary bypass in the rat.Mathematical medicine and biology : a journal of the IMA · 2017
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Ioannis SgouralisNational Institute for Mathematical and Biological Synthesis, University of Tennessee, United States. Electronic address: sgouralis@nimbios.org.
Anita T LaytonDepartment of Mathematics, Duke University, Box 90320, Durham, NC 27708, United States. Electronic address: alayton@math.duke.edu.
Duke University · USNational Institute for Mathematical and Biological Synthesis · US

Funding

Modeling Solute Transport and Urine Concentrating Mechanism in the Rat KidneyR01DK089066 · NIDDK · DUKE UNIVERSITY · PI LAYTON, ANITA · 2010 to 2014
$1.2M
NIDDK NIH HHS R01 DK089066NIDDK NIH HHS R01DK089066
6 · The paper itself

Abstract

In addition to the excretion of metabolic waste and toxin, the kidney plays an indispensable role in regulating the balance of water, electrolyte, acid-base, and blood pressure. For the kidney to maintain proper functions, hemodynamic control is crucial. In this review, we describe representative mathematical models that have been developed to better understand the kidney's autoregulatory processes. We consider mathematical models that simulate glomerular filtration, and renal blood flow regulation by means of the myogenic response and tubuloglomerular feedback. We discuss the extent to which these modeling efforts have expanded the understanding of renal functions in health and disease.

Indexed as

Models, TheoreticalHemodynamicsHumansKidneyNonlinear DynamicsRenal CirculationBlood flowGlomerular filtrationKidneyMyogenic responseNonlinear dynamicsTubuloglomerular feedback

Identifiers

PMID25765886
PMCPMC4426241
OpenAlexW2061632891

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.