ArticleBMC genomics2015
Transcriptomic response to heat stress among ecologically divergent populations of redband trout.
Article in BMC genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A meta-analysis of public RNA-Seq data identifies conserved stress responses in rainbow trout.BMC genomics · 2025Pooled it
- Neighboring Gulf Killifish (Ecology and evolution · 2026Article
- A chromosome-level genome for gila trout (Oncorhynchus gilae) provides a novel resource for conservation and management.BMC genomics · 2026Article
- Molecular signatures and machine learning driven stress biomarkers for rainbow trout aquaculture and climate adaptation.Scientific reports · 2025Article
- Environmental transcriptomics under heat stress: Can environmental RNA reveal changes in gene expression of aquatic organisms?Molecular ecology · 2025Article
- Differences in gene expression between high and low tolerance rainbow trout (Oncorhynchus mykiss) to acute thermal stress.PloS one · 2025Article
- Climate warming will test the limits of thermal plasticity in rainbow trout, a globally distributed fish.Conservation physiology · 2025Article
- Beyond latitude: thermal tolerance and vulnerability of a broadly distributed salmonid across a habitat temperature gradient.Conservation physiology · 2025Article
- A multi-tissue de novo transcriptome assembly and relative gene expression of the vulnerable freshwater salmonid Thymallus ligericus.Genetica · 2024Article
- Comparative Transcriptome Analyses Provide New Insights into the Evolution of Divergent Thermal Resistance in Two Eel Gobies.Current issues in molecular biology · 2023Article
- Muscle Transcriptome Sequencing Revealed Thermal Stress-Responsive Regulatory Genes in Farmed Rohu, Labeo rohita (Hamilton, 1822).Marine biotechnology (New York, N.Y.) · 2023Article
- Parallel adaptation to lower altitudes is associated with enhanced plasticity in Heliosperma pusillum (Caryophyllaceae).The Plant journal : for cell and molecular biology · 2023Article
- A homology guide for Pacific salmon genusEcology and evolution · 2023Article
- Whole genome resequencing identifies local adaptation associated with environmental variation for redband trout.Molecular ecology · 2023Article
- Differential transcriptomic responses to heat stress in surface and subterranean diving beetles.Scientific reports · 2022Article
- Taxifolin Modulates Transcriptomic Response to Heat Stress in Rainbow Trout,Animals : an open access journal from MDPI · 2022Article
- Applying genomics in assisted migration under climate change: Framework, empirical applications, and case studies.Evolutionary applications · 2022Review
- Draft genome of the Korean smelt Hypomesus nipponensis and its transcriptomic responses to heat stress in the liver and muscle.G3 (Bethesda, Md.) · 2021Article
- Genome-wide diversity and habitat underlie fine-scale phenotypic differentiation in the rainbow darter (Evolutionary applications · 2021Article
- Comparative transcriptomics of spotted seatrout (Ecology and evolution · 2021Article
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Authors and funding
2 authors.
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Abstract
backgroundAs ectothermic organisms have evolved to differing aquatic climates, the molecular basis of thermal adaptation is a key area of research. In this study, we tested for differential transcriptional response of ecologically divergent populations of redband trout (Oncorhynchus mykiss gairdneri) that have evolved in desert and montane climates. Each pure strain and their F1 cross were reared in a common garden environment and exposed over four weeks to diel water temperatures that were similar to those experienced in desert climates within the species' range. Gill tissues were collected from the three strains of fish (desert, montane, F1 crosses) at the peak of heat stress and tested for mRNA expression differences across the transcriptome with RNA-seq.
resultsStrong differences in transcriptomic response to heat stress were observed across strains confirming that fish from desert environments have evolved diverse mechanisms to cope with stressful environments. As expected, a large number of total transcripts (12,814) were differentially expressed in the study (FDR ≤ 0.05) with 2310 transcripts in common for all three strains, but the desert strain had a larger number of unique differentially expressed transcripts (2875) than the montane (1982) or the F1 (2355) strain. Strongly differentiated genes (>4 fold change and FDR ≤ 0.05) were particularly abundant in the desert strain (824 unique contigs) relative to the other two strains (montane = 58; F1 = 192).
conclusionsThis study demonstrated patterns of acclimation (i.e., phenotypic plasticity) within strains and evolutionary adaptation among strains in numerous genes throughout the transcriptome. Key stress response genes such as molecular chaperones (i.e., heat shock proteins) had adaptive patterns of gene expression among strains, but also a much higher number of metabolic and cellular process genes were differentially expressed in the desert strain demonstrating these biological pathways are critical for thermal adaptation to warm aquatic climates. The results of this study further elucidate the molecular basis for thermal adaptation in aquatic ecosystems and extend the potential for identifying genes that may be critical for adaptation to changing climates.
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