ArticlePublic health genomics2015
Parent and public interest in whole-genome sequencing.
Article in Public health genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Citizens' Attitudes, Knowledge, and Educational Needs in the Field of Omics Sciences: A Systematic Literature Review.Frontiers in genetics · 2020Pooled it
- Using a behaviour-change approach to support uptake of population genomic screening and management options for breast or prostate cancer.European journal of human genetics : EJHG · 2025Article
- Organizational Aspects of the Implementation and Use of Whole Genome Sequencing and Whole Exome Sequencing in the Pediatric Population in Italy: Results of a Survey.Journal of personalized medicine · 2023Article
- Australian parental perceptions of genomic newborn screening for non-communicable diseases.Frontiers in genetics · 2023Article
- How does the genomic naive public perceive whole genomic testing for health purposes? A scoping review.European journal of human genetics : EJHG · 2023Article
- Public interest in unexpected genomic findings: a survey study identifying aspects of sequencing attitudes that influence preferences.Journal of community genetics · 2022Article
- Parental Attitudes Toward Standard Newborn Screening and Newborn Genomic Sequencing: Findings From the BabySeq Study.Frontiers in genetics · 2022Article
- Attitudes towards genetic testing and information: does parenthood shape the views?Journal of community genetics · 2020Article
- What do people think about genetics? A systematic review.Journal of community genetics · 2019Review
- Public attitudes in Japan toward participation in whole genome sequencing studies.Human genomics · 2018Article
- Attitudes of stakeholders in psychiatry towards the inclusion of children in genomic research.Human genomics · 2018Article
- Parental preferences toward genomic sequencing for non-medically actionable conditions in children: a discrete-choice experiment.Genetics in medicine : official journal of the American College of Medical Genetics · 2018Article
- Marking 15 years of the Genetic and Rare Diseases Information Center.Translational science of rare diseases · 2017Article
- Public Views on Genetics and Genetic Testing: A Survey of the General Public in Belgium.Genetic testing and molecular biomarkers · 2017Article
- Parental Perspectives on Whole Exome Sequencing in Pediatric Cancer: A Typology of Perceived Utility.JCO precision oncology · 2017Article
- Preferences for the provision of whole genome sequencing services among young adults.PloS one · 2017Article
- What are people willing to pay for whole-genome sequencing information, and who decides what they receive?Genetics in medicine : official journal of the American College of Medical Genetics · 2016Article
- Parents' interest in genetic testing of their offspring in multiplex epilepsy families.Epilepsia · 2016Article
- Psychosocial Factors Influencing Parental Interest in Genomic Sequencing of Newborns.Pediatrics · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
objectiveThe aim of this study was to assess the baseline interest of the public in whole-genome sequencing (WGS) for oneself, parents' interest in WGS for their youngest children, and factors associated with such interest.
methodsA random sample of adults from a probability-based nationally representative online panel was surveyed. All participants were provided basic information about WGS and then asked about their interest in WGS for themselves. Those participants who were parents were additionally asked about their interest in WGS for their children. The order in which parents were asked about their interest in WGS for themselves and for their child was randomized. The relationship between parent/child characteristics and interest in WGS was examined.
resultsThe overall response rate was 62% (55% among parents). 58.6% of the total population (parents and nonparents) was interested in WGS for themselves. Similarly, 61.8% of the parents were interested in WGS for themselves and 57.8% were interested in WGS for their youngest children. Of note, 84.7% of the parents showed an identical interest level in WGS for themselves and their youngest children. Mothers as a group and parents whose youngest children had ≥2 health conditions had significantly more interest in WGS for themselves and their youngest children, while those with conservative political ideologies had considerably less.
conclusionsWhile US adults have varying interest levels in WGS, parents appear to have similar interests in genome testing for themselves and their youngest children. As WGS technology becomes available in the clinic and private market, clinicians should be prepared to discuss WGS risks and benefits with their patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.