ArticleeLife2015
Nuclear genomic signals of the 'microturbellarian' roots of platyhelminth evolutionary innovation.
Article in eLife, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.
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Who cites it
79 citing papers in PubMed.
- Genomic Exaptation and Regulatory Landscape Shifts as Key Mechanisms Enabling Flatworm Terrestrialization.Genome biology and evolution · 2026Article
- Unusual inheritance of a functionalScience advances · 2025Article
- Evolution of SL-RNA Genes and Their Splicing Targets in Parasitic Flatworms.Molecular biology and evolution · 2025Article
- Signals from the head and germinative region differentially regulate regeneration competence of the tapeworm Hymenolepis diminuta.Development (Cambridge, England) · 2025Article
- Signals from the head and germinative region differentially regulate regeneration competence of the tapewormbioRxiv : the preprint server for biology · 2025Article
- The Ultrastructure of the Apical Organ of the Goette's Larvae of the Polyclad Flatworm Stylochus pilidium Indicates Homology Between Polyclad Larvae.Cell biology international · 2025Article
- Evolutionary History of Bilaterian FoxP Genes: Complex Ancestral Functions and Evolutionary Changes Spanning 2R-WGD in the Vertebrate Lineage.Molecular biology and evolution · 2025Article
- Phylogenetic history of the acquisition of molluscan hosts in acotylean flatworms.Biology letters · 2025Article
- Evidence for Multiple Independent Expansions of Fox Gene Families Within Flatworms.Journal of molecular evolution · 2025Article
- Regeneration in the absence of canonical neoblasts in an early branching flatworm.Nature communications · 2025Article
- Evaluating topological variability in Neodermata phylogenies using mitochondrial and ribosomal gene markers.PloS one · 2025Article
- A comparative analysis of planarian genomes reveals regulatory conservation in the face of rapid structural divergence.Nature communications · 2024Article
- Ultrastructural analysis and 3D reconstruction of the frontal sensory-glandular complex and its neural projections in the platyhelminth Macrostomum lignano.Cell and tissue research · 2024Article
- Metabolites play an underappreciated role in development.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Regeneration in the absence of canonical neoblasts in an early branching flatworm.bioRxiv : the preprint server for biology · 2024Article
- Flatworm Transcriptomes Reveal Widespread Parasitism by Histophagous Ciliates.Genome biology and evolution · 2024Article
- Evolutionary dynamics of whole-body regeneration across planarian flatworms.Nature ecology & evolution · 2023Article
- Patterns of host-parasite associations between marine meiofaunal flatworms (Platyhelminthes) and rhytidocystids (Apicomplexa).Scientific reports · 2023Article
- Convergent evolution of the sensory pits in and within flatworms.BMC biology · 2023Article
- Article
19 more citing papers are in PubMed but not listed here.
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3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Flatworms number among the most diverse invertebrate phyla and represent the most biomedically significant branch of the major bilaterian clade Spiralia, but to date, deep evolutionary relationships within this group have been studied using only a single locus (the rRNA operon), leaving the origins of many key clades unclear. In this study, using a survey of genomes and transcriptomes representing all free-living flatworm orders, we provide resolution of platyhelminth interrelationships based on hundreds of nuclear protein-coding genes, exploring phylogenetic signal through concatenation as well as recently developed consensus approaches. These analyses robustly support a modern hypothesis of flatworm phylogeny, one which emphasizes the primacy of the often-overlooked 'microturbellarian' groups in understanding the major evolutionary transitions within Platyhelminthes: perhaps most notably, we propose a novel scenario for the interrelationships between free-living and vertebrate-parasitic flatworms, providing new opportunities to shed light on the origins and biological consequences of parasitism in these iconic invertebrates.
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