ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2015
Characterization and Comparison of Protein and Peptide Profiles and their Biological Activities of Improved Common Bean Cultivars (Phaseolus vulgaris L.) from Mexico and Brazil.
Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 87 citations in OpenAlex.
- Antioxidant Activity and Resistance Against Oxidation of Peptide Fractions from Common Bean (Antioxidants (Basel, Switzerland) · 2026Article
- Potential Human Health Benefits ofNutrients · 2024Article
- Nutritional Characterization of Chilean Landraces of Common Bean.Plants (Basel, Switzerland) · 2024Article
- Impact of foliar spray with Se, nano-Se and sodium sulfate on growth, yield and metabolic activities of red kidney bean.Scientific reports · 2023Article
- In vitro Digestion ofFoods (Basel, Switzerland) · 2023Article
- In Vitro Assessment Methods for Antidiabetic Peptides from Legumes: A Review.Foods (Basel, Switzerland) · 2023Review
- Nutritional, functional, and bioactive properties of african underutilized legumes.Frontiers in plant science · 2023Review
- Bioactive Peptides Obtained from Legume Seeds as New Compounds in Metabolic Syndrome Prevention and Diet Therapy.Foods (Basel, Switzerland) · 2022Review
- Common bean (Phaseolus vulgaris L.) α-amylase inhibitors as safe nutraceutical strategy against diabetes and obesity: An update review.Phytotherapy research : PTR · 2022Review
- Legume Proteins and Peptides as Compounds in Nutraceuticals: A Structural Basis for Dietary Health Effects.Nutrients · 2022Review
- Antioxidant and Cytotoxic Activities of Kudzu Roots and Soy Molasses against Pediatric Tumors and Phytochemical Analysis of Isoflavones Using HPLC-DAD-ESI-HRMS.Plants (Basel, Switzerland) · 2022Article
- Sensory and Biological Potential of Encapsulated Common Bean Protein Hydrolysates Incorporated in a Greek-Style Yogurt Matrix.Polymers · 2022Article
- Phytochemical Investigation of Bioactive Compounds from White Kidney Beans (Fruits ofPlants (Basel, Switzerland) · 2021Article
- Forty-One Plant Extracts Screened for Dual Antidiabetic and Antioxidant Functions: Evaluating the Types of Correlation between -Amylase Inhibition and Free Radical Scavenging.Molecules (Basel, Switzerland) · 2021Article
- Common Bean (Plants (Basel, Switzerland) · 2019Article
- The Epigenetic Connection Between the Gut Microbiome in Obesity and Diabetes.Frontiers in genetics · 2019Review
- Biochemical Properties of α-Amylase from Midgut of Alphitobius diaperinus (Panzer) (Coleoptera: Tenebrionidae) Larvae.Neotropical entomology · 2018Article
- Altered Gut Microbiota and Compositional Changes inFrontiers in microbiology · 2018Article
- Protein and Metalloprotein Distribution in Different Varieties of Beans (International journal of food science · 2017Article
- Antioxidant and Anticancer Activities of Walnut (Juglans regia L.) Protein Hydrolysates Using Different Proteases.Plant foods for human nutrition (Dordrecht, Netherlands) · 2016Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Common bean (Phaseolus vulgaris L.) is a good source of protein, vitamins, minerals and complex carbohydrates. The objective was to compare protein profile, including anti-nutrient proteins, and potential bioactive peptides of improved common bean cultivars grown in Mexico and Brazil. Bean protein isolates (BPI) were prepared from 15 common bean cultivars and hydrolyzed using pepsin/pancreatin. Thirteen proteins were identified by SDS-PAGE and protein in-gel tryptic-digestion-LC/MS. Protein profile was similar among common bean cultivars with high concentrations of defense-related proteins. Major identified proteins were phaseolin, lectin, protease and α-amylase inhibitors. Lectin (159.2 to 357.9 mg lectin/g BPI), Kunitz trypsin inhibitor (inh) (4.3 to 75.5 mg trypsin inh/g BPI), Bowman-Birk inhibitor (5.4 to 14.3 μg trypsin-chymotrypsin inh/g BPI) and α-amylase inhibitor activity (2.5 to 14.9% inhibition relative to acarbose/mg BPI) were higher in Mexican beans compared to Brazilian beans. Abundant peptides were identified by HPLC-MS/MS with molecular masses ranging from 300 to 1500 Da and significant sequences were SGAM, DSSG, LLAH, YVAT, EPTE and KPKL. Potential bioactivities of sequenced peptides were angiotensin converting enzyme inhibitor (ACE), dipeptidyl peptidase IV inhibitor (DPP-IV) and antioxidant capacity. Peptides from common bean proteins presented potential biological activities related to control of hypertension and type-2 diabetes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.