ArticleOperative dentistry
Increased Durability of Resin-Dentin Bonds Following Cross-Linking Treatment.
Article in Operative dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Pooled it
- Effect of collagen cross-linkers on dentin bond strength: A systematic review and network meta-analysis.Frontiers in bioengineering and biotechnology · 2022Pooled it
- Mechanisms regulating the degradation of dentin matrices by endogenous dentin proteases and their role in dental adhesion. A review.American journal of dentistry · 2014Pooled it
- A dual action approach of B-type proanthocyanidins for silencing enzymatic activity and sealing natural caries-affected dentin-resin interfaces.Journal of dentistry · 2025Article
- Effect of Carbodiimide (EDC) on the Bond Strength Longevity of Epoxy Resin-based Endodontic Sealer to Root Dentin: An In-Vitro Study.The journal of adhesive dentistry · 2023Article
- Can Carbodiimide (EDC) and Chitosan Cross-linking Agents Effect the Longevity of Fiberglass Posts Luted with Different Types of Composite Cements to Root Dentin?The journal of adhesive dentistry · 2023Article
- Biodegradation of Dental Resin-Based Composite-A Potential Factor Affecting the Bonding Effect: A Narrative Review.Biomedicines · 2022Review
- Influence of two carbodiimides on the bond strength of universal adhesives to dentin.Odontology · 2022Article
- Effects of carbodiimide combined with ethanol-wet bonding pretreatment on dentin bonding properties: anPeerJ · 2022Article
- Effect of different solutions in reversing the damage caused by radiotherapy in dentin structure.Medicina oral, patologia oral y cirugia bucal · 2020Article
- Effect of dentin biomodifiers on the immediate and long-term bond strengths of a simplified etch and rinse adhesive to dentin.Restorative dentistry & endodontics · 2017Article
- [Progress on matrix metalloproteinase inhibitors].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2017Article
- Influence of EDC on Dentin-Resin Shear Bond Strength and Demineralized Dentin Thermal Properties.Materials (Basel, Switzerland) · 2016Article
- Experimental primers containing synthetic and natural compounds reduce enzymatic activity at the dentin-adhesive interface under cyclic loading.Dental materials : official publication of the Academy of Dental Materials · 2016Article
- Transdentinal cytotoxicity of glutaraldehyde on odontoblast-like cells.Journal of dentistry · 2015Article
- Effect of EDTA Conditioning and Carbodiimide Pretreatment on the Bonding Performance of All-in-One Self-Etch Adhesives.International journal of dentistry · 2015Article
- Effect of carbodiimide on the structural stability of resin/dentin interface.Journal of conservative dentistry : JCDReview
- Phosphoric acid containing proanthocyanidin enhances bond stability of resin/dentin interface.Brazilian dental journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
objectivesThis study evaluated the long-term effect of carbodiimide treatments of acid-etched dentin on resin-dentin bond strength of a simplified etch-and-rinse adhesive system.
methodsForty-eight sound third molars were divided into three groups (n=16) according to the dentin treatment: G1: deionized water; G2: 0.5 mol/L 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) applied for 30 seconds; and G3: 0.5 mol/L EDC applied for 60 seconds. Flat dentin surfaces were produced, etched with 37% phosphoric acid for 15 seconds, and then treated with deionized water for 60 seconds or with 0.5 mol/L EDC for 30 or 60 seconds prior to the application of Single Bond 2. Crowns were restored with resin composite, and beam specimens were prepared for microtensile testing. The beams from each group were tested 24 hours or 6 or 12 months after the adhesive procedures. One slab from each tooth was prepared and analyzed for nanoleakage. Bond strength (MPa) data were submitted to analysis of variance and Tukey test (α=0.05).
resultsThe treatment of dentin with 0.5 mol/L EDC for 30 seconds (24.1±6.2 MPa) and 60 seconds (25.5±5.1 MPa) did not negatively affect the immediate bond strength of Single Bond 2 when compared to the control group (24.6±7.3 MPa). Additionally, EDC prevented resin-dentin bond degradation after 12 months in artificial saliva for both periods of treatment. An increased accumulation of silver ions was seen for the control group over time, while a much lower amount of silver grains was observed for the EDC-treated groups.
conclusions0.5 mol/L EDC was able to prevent resin-dentin bond degradation after 12 months, especially when applied for 60 seconds.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.