Evidence map›Paper›PMID 25763690›Full record

ReviewPlant signaling & behavior2014

Cardiolipin at the heart of stress response across kingdoms.

Rosine de Paepe, Stéphane D Lemaire, Antoine Danon

Open access · bronzeAbstract readReview
In one paragraph

Review in Plant signaling & behavior, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. The Effect of pH on the Structure and Lateral Organization of Cardiolipin in Langmuir Monolayers.Chemphyschem : a European journal of chemical physics and physical chemistry · 2022
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Rosine de Paepea Institut de Biologie des Plantes; Saclay Plant Science; Université de Paris-Sud XI; CNRS; UMR 8618; Orsay Cedex, France.
Stéphane D Lemaire
Antoine Danon
Université Claude Bernard Lyon 1 · FRUniversité Paris-Sud · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiolipin is a key phospholipid most specifically found in the membrane of mitochondria in yeasts, plants, and animals. Cardiolipins are essential for the maintenance, the integrity, and the dynamics of mitochondria. In most eukaryotes mitochondria play a central role in the response and adaptation to stress conditions especially through their importance in the control of programmed cell death. To assess the impact of the absence of cardiolipin, knock-down of the expression of cardiolipin synthase, the last enzyme of cardiolipin synthesis pathway in eukaryotes has been performed in yeasts, animals, and plants. These studies showed that cardiolipin is not only important for mitochondrial ultrastructure and for the stability of respiratory complexes, but it is also a key player in the response to stress, the formation of reactive oxygen species, and the execution of programmed cell death.

Indexed as

AnimalsApoptosisCardiolipinsCytochromes cGene Knockdown TechniquesMembrane ProteinsMitochondriaMutationPlantsReactive Oxygen SpeciesSignal TransductionStress, PhysiologicalTransferases (Other Substituted Phosphate Groups)YeastsCardiolipinscardiolipin synthetaseCytochromes cMembrane ProteinsReactive Oxygen SpeciesTransferases (Other Substituted Phosphate Groups)cardiolipinmitochondriaprogrammed cell deathreactive oxygen speciesstress

Identifiers

PMID25763690
PMCPMC4203511
OpenAlexW1987088119

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.