Evidence map›Paper›PMID 25763674›Full record

Observational studySexually transmitted diseases2015

Molecular genotyping of human papillomavirus l1 gene in low-risk and high-risk populations in Bangkok.

Pornsawan Leaungwutiwong, Busara Bamrungsak, Akanitt Jittmittraphap, Pannamas Maneekan, Nathamon Kosoltanapiwat, Thareerat Kalambaheti, James F Kelley

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Sexually transmitted diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Expression Pattern of Genes in Condyloma Acuminata Treated withEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Pornsawan LeaungwutiwongFrom the *Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; †Sexually Transmitted Infections Cluster (Bangrak Hospital), Bureau of AIDS, TB and STIs, Department of Disease Control, Ministry of Public Health, Bangkok, Thailand; ‡Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; and §Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI.
Busara Bamrungsak
Akanitt Jittmittraphap
Pannamas Maneekan
Nathamon Kosoltanapiwat
Thareerat Kalambaheti
James F Kelley
Mahidol University · THMahidol Oxford Tropical Medicine Research Unit · THMinistry of Public Health · THUniversity of Hawaiʻi at Mānoa · US

Funding

Small Grants ProgramP30GM114737 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI DENG, YOUPING · 2015 to 2022
$8.1M
Pacific Center for Emerging Infectious Diseases ResearchP20GM103516 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI YANAGIHARA, RICHARD · 2012 to 2014
$6.1M
Northern/Pacific Universities Global Health Research Training ConsortiumR25TW009345 · FIC · UNIVERSITY OF WASHINGTON · PI KOLARS, JOSEPH C., NERURKAR, VIVEK RAMCHANDRA · 2012 to 2016
$5.9M
FIC NIH HHS R25 TW009345FIC NIH HHS R25TW009345NIGMS NIH HHS P20 GM103516NIGMS NIH HHS P20GM103516NIGMS NIH HHS P30 GM114737
6 · The paper itself

Abstract

backgroundHuman papillomavirus (HPV) infections in Thailand are a public health concern, but information on HPV infection in sex workers and men who have sex with men (MSM) is limited. The aim of this study was to measure the prevalence and genotype distribution of HPV among low- and high-risk, HIV-negative populations.

methodsA total of 300 participants were categorized as general women, female sex workers, MSM, and MSM sex workers. Human papillomavirus infections were identified by the Papanicolaou test and nested polymerase chain reaction. A phylogenetic analysis of partial HPV L1 genes was performed.

resultsAbnormal cytology was found in 5% of general women, 10% of female sex workers, 24% of MSM, and 28% of MSM sex workers. Human papillomavirus was detected in 9% of general women, 13% of female sex workers, and 30% in both MSM and the MSM sex workers. The prevalence of HPV high-risk genotypes was significantly higher in female sex workers and MSM, whereas low-risk genotypes and genital warts were significantly higher in MSM sex workers. Significantly more patients with genital warts and cervical intraepithelial neoplasia I/anal intraepithelial neoplasia I harbored low-risk genotypes, whereas those with cervical intraepithelial neoplasia II/anal intraepithelial neoplasia II harbored high-risk genotypes.

conclusionsHigh- and low-risk HPV genotypes persist in high-risk groups in Bangkok. Some genotypes infecting at-risk populations are not vaccine preventable. These findings may help to elucidate the prevalence of HPV infections in Thailand and serve as the basis for additional investigations into risk factors for these populations.

Indexed as

HeterosexualityHomosexuality, MaleSex WorkersAdultCapsid ProteinsCross-Sectional StudiesDNA, ViralFemaleGenotypeGenotyping TechniquesHuman Papillomavirus DNA TestsHumansMaleOncogene Proteins, ViralPapillomavirus InfectionsPhylogenyCapsid ProteinsDNA, ViralHPV L1 protein, Human papillomavirusOncogene Proteins, Viral

Identifiers

PMID25763674
PMCPMC4358745
OpenAlexW2044525607

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.