Evidence map›Paper›PMID 25763571›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2016

A prospective investigation of predictive parameters for post-surgical recurrences in sinonasal polyposis.

Giuseppe Brescia, Gino Marioni, Sebastiano Franchella, Giulia Ramacciotti, Luciano Giacomelli, Filippo Marino, Alessandro Martini

Abstract read
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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 44 citations in OpenAlex.

  1. Trial
  2. Immune Clues to Sinus Blues: Linking Biomarkers to Radiologic Score of Rhinosinusitis.World journal of otorhinolaryngology - head and neck surgery · 2026
    Article
  3. Review
  4. How to Identify Type 2 Chronic Rhinosinusitis in East Asian Patients.Journal of rhinology : official journal of the Korean Rhinologic Society · 2026
    Review
  5. Article
  6. Article
  7. Patterns of recurrence in patients with CRSwNP who underwent complete FESS.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. The Comparison of Inflammatory Markers for the Prediction of Recurrence of the Nasal Polyp After Endoscopic Sinus Surgery.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Giuseppe BresciaOtolaryngology Section, Department of Neurosciences DNS, Padova University, Via Giustiniani 2, 35128, Padua, Italy. giuseppe.brescia@sanita.padova.it.
Gino MarioniOtolaryngology Section, Department of Neurosciences DNS, Padova University, Via Giustiniani 2, 35128, Padua, Italy.
Sebastiano FranchellaOtolaryngology Section, Department of Neurosciences DNS, Padova University, Via Giustiniani 2, 35128, Padua, Italy.
Giulia RamacciottiOtolaryngology Section, Department of Neurosciences DNS, Padova University, Via Giustiniani 2, 35128, Padua, Italy.
Luciano GiacomelliDepartment of Medicine DIMED, Padova University, Padua, Italy.
Filippo MarinoDepartment of Medicine DIMED, Padova University, Padua, Italy.
Alessandro MartiniOtolaryngology Section, Department of Neurosciences DNS, Padova University, Via Giustiniani 2, 35128, Padua, Italy.
University of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Even after appropriate surgical therapy, a significant number of patients with chronic rhinosinusitis with nasal polyps (CRSwNP) experience recurrences. The end-point of this prospective study was to apply univariate and multivariate statistical models to identify clinical, pathological, and laboratory variables that could predict CRSwNP recurrence after endoscopic sinus surgery. The study enrolled 143 patients between 2010 and 2013, who were all treated by the same surgeon for CRSwNP. Twenty-one patients developed recurrent polyposis. The recurrence rate was significantly higher for the eosinophilic than for the non-eosinophilic type (p = 0.020). Among the patients who developed a recurrence, the disease-free interval was significantly shorter for those with eosinophilic-type polyposis (p = 0.003). Univariate statistical analysis disclosed significant associations between CRSwNP recurrence and age (p = 0.035), allergy (p = 0.014), and eosinophilic granulomatosis with polyangiitis (p = 0.01). The multivariate model showed that only histological evidence of the eosinophilic type of CRSwNP retained an independent prognostic significance in relation to recurrent polyposis (p = 0.033). Judging from our results, it is reasonable to consider both stricter follow-up protocols and postoperative adjuvant medical treatments for patients with a histological diagnosis of eosinophilic-type CRSwNP.

Indexed as

Nasal PolypsNatural Orifice Endoscopic SurgeryParanasal Sinus NeoplasmsRhinitisSinusitisChronic DiseaseFemaleHumansMaleMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingParanasal SinusesPostoperative PeriodPrognosisProspective StudiesEosinophilic polypsPrognosisRecurrenceSinonasal polyposis

Identifiers

PMID25763571
OpenAlexW2013504734

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.