Evidence map›Paper›PMID 25763558›Full record

ArticleCancer2015

Public health impact of achieving 80% colorectal cancer screening rates in the United States by 2018.

Reinier G S Meester, Chyke A Doubeni, Ann G Zauber, S Luuk Goede, Theodore R Levin, Douglas A Corley, Ahmedin Jemal, Iris Lansdorp-Vogelaar

Open access · bronzeAbstract read
In one paragraph

Article in Cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
114citing papers in PubMed, 6 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

114 citing papers in PubMed, 6 syntheses or guidelines pooled it, 207 citations in OpenAlex.

  1. Pooled it
  2. NCCN Guidelines Insights: Colorectal Cancer Screening, Version 2.2020.Journal of the National Comprehensive Cancer Network : JNCCN · 2020
    Guideline
  3. Systematic Review of the Cost Effectiveness of Breast Cancer Prevention, Screening, and Treatment Interventions.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2020
    Pooled it
  4. Pooled it
  5. Use of NCCN Guidelines, Other Guidelines, and Biomarkers for Colorectal Cancer Screening.Journal of the National Comprehensive Cancer Network : JNCCN · 2016
    Guideline
  6. Pooled it
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  14. Repeat Annual Colorectal Cancer Screening in Rural Community Clinics: A Randomized Clinical Trial to Evaluate Outreach Strategies to Sustain Screening.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2020
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  19. Efficacy of a Telehealth Intervention on Colonoscopy Uptake When Cost Is a Barrier: The Family CARE Cluster Randomized Controlled Trial.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2015
    Trial
  20. Article

54 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Reinier G S MeesterDepartment of Public Health, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Chyke A DoubeniDepartment of Family Medicine and Community Health, and the Department of Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Ann G ZauberDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.
S Luuk GoedeDepartment of Public Health, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Theodore R LevinDivision of Research, Kaiser Permanente, Oakland, California.
Douglas A CorleyDivision of Research, Kaiser Permanente, Oakland, California.
Ahmedin JemalSurveillance and Health Services Research, American Cancer Society, Atlanta, Georgia.
Iris Lansdorp-VogelaarDepartment of Public Health, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Erasmus MC · NLKaiser Permanente · USAmerican Cancer Society · USCommunity Initiatives · USMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
CRN4: Cancer Research Resources & Collaboration in Integrated Health Care SystemsU24CA171524 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI KUSHI, LAWRENCE H · 2012 to 2016
$16.0M
Optimizing the use of colonoscopy for CRC screening in a large community-basedU54CA163262 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI CORLEY, DOUGLAS ALLEN, DOUBENI, CHYKE ABADAMA · 2011 to 2017
$9.6M
Modeling Effective Health Policies for Colorectal CancerU01CA152959 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI KUNTZ, KAREN M, LANSDORP-VOGELAAR, IRIS · 2010 to 2014
$5.4M
Effectiveness of Screening Colonoscopy in Reducing Deaths from Colorectal CancerU01CA151736 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI DOUBENI, CHYKE ABADAMA · 2011 to 2015
$4.5M
NCI NIH HHS P30 CA008748NCI NIH HHS U01 CA151736NCI NIH HHS U01 CA152959NCI NIH HHS U24 CA171524NCI NIH HHS U54 CA163262
6 · The paper itself

Abstract

backgroundThe National Colorectal Cancer Roundtable, a national coalition of public, private, and voluntary organizations, has recently announced an initiative to increase colorectal cancer (CRC) screening rates in the United States to 80% by 2018. The authors evaluated the potential public health benefits of achieving this goal.

methodsThe authors simulated the 1980 through 2030 United States population of individuals aged 50 to 100 years using microsimulation modeling. Test-specific historical screening rates were based on National Health Interview Survey data for 1987 through 2013. The effects of increasing screening rates from approximately 58% in 2013 to 80% in 2018 were compared to a scenario in which the screening rate remained approximately constant. The outcomes were cancer incidence and mortality rates and numbers of CRC cases and deaths during short-term follow-up (2013-2020) and extended follow-up (2013-2030).

resultsIncreasing CRC screening rates to 80% by 2018 would reduce CRC incidence rates by 17% and mortality rates by 19% during short-term follow-up and by 22% and 33%, respectively, during extended follow-up. These reductions would amount to a total of 277,000 averted new cancers and 203,000 averted CRC deaths from 2013 through 2030.

conclusionsAchieving the goal of increasing the uptake of CRC screening in the United States to 80% by 2018 may have a considerable public health impact by averting approximately 280,000 new cancer cases and 200,000 cancer deaths within <20 years. Cancer 2015;121:2281-2285. © 2015 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

Indexed as

Colorectal NeoplasmsEarly Detection of CancerFemaleHumansIncidenceMaleMass ScreeningPublic HealthTime FactorsUnited Statescancer screeningcolorectal neoplasmsincidencemortalitypublic health

Identifiers

PMID25763558
PMCPMC4567966
OpenAlexW1861085621

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.