Evidence map›Paper›PMID 25763362›Full record

ArticleGerms2015

Occurrence of HBV/HIV coinfection by laboratory values in Roma, Lesotho.

Eltony Mugomeri, Mamakoli Blandina Senauoane, Vurayai Ruhanya, Nyasha Chin'ombe, George Nyandoro

Abstract read
In one paragraph

Article in Germs, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eltony MugomeriMTech, Department of Pharmacy, National University of Lesotho, Maseru, Lesotho.
Mamakoli Blandina SenauoaneBSc, Department of Nursing, National University of Lesotho, Maseru, Lesotho.
Vurayai RuhanyaMSc, Department of Medical Microbiology, University of Zimbabwe, Avondale, Harare, Zimbabwe.
Nyasha Chin'ombePhD, Department of Medical Microbiology, University of Zimbabwe, Avondale, Harare, Zimbabwe.
George NyandoroMSc, Department of Medical Microbiology, University of Zimbabwe, Avondale, Harare, Zimbabwe;

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study was an assessment of the coinfection status of patients with human immunodeficiency virus (HIV) and hepatitis B virus (HBV) in Lesotho, and this has been rarely reported.

methodsThis was a retrospective study, in a laboratory setting, on HBV/HIV coinfection among 304 HIV-positive patients who were screened for HBsAg in St Joseph's Hospital records between March 2011 and December 2013. Demographic characteristics, HIV status, indications for HBsAg screening, HBsAg results and liver function test results including alanine transaminase (ALT), aspartate transaminase (AST) and alkaline phosphatase were reviewed from the patient and laboratory registers.

resultsIn this study 10.5% of 304 HIV-positive patients had HBV/HIV coinfection. With respect to gender, males had a significantly higher (p=0.048) rate of HBV/HIV coinfection in this study. Increased levels of ALT (p=0.013) and AST (p=0.014) were significantly associated with HBV/HIV coinfection status.

conclusionGender and liver function tests are important predictors for HBV/HIV coinfection. Screening for HBV coinfection in HIV-positive patients is recommended.

Indexed as

HBsAgHepatitis BHIVLesotho

Identifiers

PMID25763362
PMCPMC4350861

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.