Evidence map›Paper›PMID 25763264›Full record

ArticleIranian Red Crescent medical journal2015

Treatment of Alzheimer's disease in Iranian traditional medicine.

Mohammad Mahdi Ahmadian-Attari, Abolhassan Ahmadiani, Mohammad Kamalinejad, Leila Dargahi, Meysam Shirzad, Mahmoud Mosaddegh

Open access · greenAbstract read
In one paragraph

Article in Iranian Red Crescent medical journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  3. The Effects ofInternational journal of preventive medicine · 2018
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  6. Avicenna journal of phytomedicine
    Review
  7. Evaluation of the Effectiveness of an Herbal Formulation ofJournal of research in pharmacy practice
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mohammad Mahdi Ahmadian-AttariDepartment of Traditional Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.
Abolhassan AhmadianiNeurobiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran ; Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran ; Department of Pharmacology, University of Malaya, Kuala Lumpur, Malaysia.
Mohammad KamalinejadDepartment of Pharmacognosy, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.
Leila DargahiNeurobiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran ; Neuroscience Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.
Meysam ShirzadDepartment of Traditional Medicine, Tehran University of Medical Sciences, Tehran, IR Iran.
Mahmoud MosaddeghDepartment of Traditional Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.
Shahid Beheshti University of Medical Sciences · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlzheimer's disease (AD) is a progressive neurodegenerative disease with a high prevalence in recent years. Dramatic growth in AD prevalence has increased the importance of more researches on AD treatment. History has shown that traditional medicine can be a source of inspiration to find new therapies.

objectivesThis study tried to codify the recommendations of Iranian traditional medicine (ITM) by studying the main medical manuscripts. The second purpose was to compare these findings with new medical information. MATERIALS AND

methodsCardinal traditional medical and pharmacological texts from 10th to 18th century were searched for traditional terms of dementia (Nesyan, Fisad-uz-Zekr, Faramooshkari) focused on treatment methods. The findings were classified into three groups: lifestyle recommendations, dietary approaches, and drug therapies. These findings were compared with new medical findings.

resultsITM has dietary recommendations for dementia such as increasing consumption of nuts, poultry and eggs, milk, and grape products (like raisin and currant). These compounds are full of unsaturated fatty acids, cholesterol, and polyphenolic compounds. New findings suggest that these substances can help in prevention and treatment of AD. ITM has some lifestyle considerations like increasing physical and mental activities, listening to music, attending musical feasts, and smelling specific perfumes. New medical findings confirm nearly all of these recommendations. Along with the aforementioned items, treatment with natural medicines is in the first line of traditional treatment of dementia. New investigations show that many of these herbs have antioxidant, anti-inflammatory factors and acetylcholine esterase inhibitory effects. A few of them also have N-methyl-D-aspartate (NMDA) blocking activity. When these herbs are put together in traditional formulations, they can comprehensively fight against the disease.

conclusionsMore ethnopharmacological and ethnomedical studies on ITM antidementia therapy can be followed by fruitful results.

Indexed as

Alzheimer’s DiseaseDietLifestyleTraditional Medicine

Identifiers

PMID25763264
PMCPMC4341360
OpenAlexW2132545491

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.