Evidence map›Paper›PMID 25763174›Full record

ArticleElectronic physician

Explanation-aware computing of the prognosis for breast cancer supported by IK-DCBRC: Technical innovation.

Abdeldjalil Khelassi

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Article in Electronic physician. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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2 citing papers in PubMed.

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5 · Who and what money

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1 author.

Abdeldjalil KhelassiD.Sc. in Computer Science, Associate Professor, Department of Informatics, Faculty of Sciences, Tlemcen University, Tlemcen, Algeria ; Head of Knowledge and Information Engineering Research Team KIERT, Informatics Research Laboratory IRL, Tlemcen University, Tlemcen, Algeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundActive research is being conducted to determine the prognosis for breast cancer. However, the uncertainty is a major obstacle in this domain of medical research. In that context, explanation-aware computing has the potential for providing meaningful interactions between complex medical applications and users, which would ensure a significant reduction of uncertainty and risks. This paper presents an explanation-aware agent, supported by Intensive Knowledge-Distributed Case-Based Reasoning Classifier (IK-DCBRC), to reduce the uncertainty and risks associated with the diagnosis of breast cancer.

methodsA meaningful explanation is generated by inferring from a rule-based system according to the level of abstraction and the reasoning traces. The computer-aided detection is conducted by IK-DCBRC, which is a multi-agent system that applies the case-based reasoning paradigm and a fuzzy similarity function for the automatic prognosis by the class of breast tumors, i.e. malignant or benign, from a pattern of cytological images.

resultsA meaningful interaction between the physician and the computer-aided diagnosis system, IK-DCBRC, is achieved via an intelligent agent. The physician can observe the trace of reasoning, terms, justifications, and the strategy to be used to decrease the risks and doubts associated with the automatic diagnosis. The capability of the system we have developed was proven by an example in which conflicts were clarified and transparency was ensured.

conclusionThe explanation agent ensures the transparency of the automatic diagnosis of breast cancer supported by IK-DCBRC, which decreases uncertainty and risks and detects some conflicts.

Indexed as

breast cancer prognosiscase-based reasoningcomputer-aided diagnosisexplanation-aware computingmulti-agent system

Identifiers

PMID25763174
PMCPMC4324263

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.