ArticleFrontiers in plant science2015
Non-specific phospholipase C4 mediates response to aluminum toxicity in Arabidopsis thaliana.
Article in Frontiers in plant science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 30 citations in OpenAlex.
- Imaging Plant Lipids with Fluorescent Reporters.Plants (Basel, Switzerland) · 2024Review
- Dissection of genetic architecture of nine hazardous component traits of mainstream smoke in tobacco (Frontiers in plant science · 2024Article
- Phospholipase C: Diverse functions in plant biotic stress resistance and fungal pathogenicity.Molecular plant pathology · 2023Review
- DIACYLGLYCEROL KINASE 5 participates in flagellin-induced signaling in Arabidopsis.Plant physiology · 2022Article
- The functions of phospholipases and their hydrolysis products in plant growth, development and stress responses.Progress in lipid research · 2022Review
- Dynamic Changes in Membrane Lipid Metabolism and Antioxidant Defense During Soybean (Frontiers in plant science · 2022Article
- Emerging role of phospholipase C mediated lipid signaling in abiotic stress tolerance and development in plants.Plant cell reports · 2021Review
- Nonspecific phospholipase C4 hydrolyzes phosphosphingolipids and sustains plant root growth during phosphate deficiency.The Plant cell · 2021Article
- Phospholipases C and D and Their Role in Biotic and Abiotic Stresses.Plants (Basel, Switzerland) · 2021Review
- Genomic-Wide Analysis of the PLC Family and Detection of GmPI-PLC7 Responses to Drought and Salt Stresses in Soybean.Frontiers in plant science · 2021Article
- Non-specific phospholipase C (NPC): an emerging class of phospholipase C in plant growth and development.Journal of plant research · 2020Review
- Plant-UniquePlants (Basel, Switzerland) · 2019Article
- Recent Advances in the Cellular and Developmental Biology of Phospholipases in Plants.Frontiers in plant science · 2019Review
- The Arabidopsis thaliana non-specific phospholipase C2 is involved in the response to Pseudomonas syringae attack.Annals of botany · 2018Article
- Structural, expression and evolutionary analysis of the non-specific phospholipase C gene family in Gossypium hirsutum.BMC genomics · 2017Article
- Arabidopsis non-specific phospholipase C1: characterization and its involvement in response to heat stress.Frontiers in plant science · 2015Article
- Aluminum ions alter the function of non-specific phospholipase C through the changes in plasma membrane physical properties.Plant signaling & behavior · 2015Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aluminum ions (Al) have been recognized as a major toxic factor for crop production in acidic soils. The first indication of the Al toxicity in plants is the cessation of root growth, but the mechanism of root growth inhibition is largely unknown. Here we examined the impact of Al on the expression, activity, and function of the non-specific phospholipase C4 (NPC4), a plasma membrane-bound isoform of NPC, a member of the plant phospholipase family, in Arabidopsis thaliana. We observed a lower expression of NPC4 using β-glucuronidase assay and a decreased formation of labeled diacylglycerol, product of NPC activity, using fluorescently labeled phosphatidylcholine as a phospholipase substrate in Arabidopsis WT seedlings treated with AlCl3 for 2 h. The effect on in situ NPC activity persisted for longer Al treatment periods (8, 14 h). Interestingly, in seedlings overexpressing NPC4, the Al-mediated NPC-inhibiting effect was alleviated at 14 h. However, in vitro activity and localization of NPC4 were not affected by Al, thus excluding direct inhibition by Al ions or possible translocation of NPC4 as the mechanisms involved in NPC-inhibiting effect. Furthermore, the growth of tobacco pollen tubes rapidly arrested by Al was partially rescued by the overexpression of AtNPC4 while Arabidopsis npc4 knockout lines were found to be more sensitive to Al stress during long-term exposure of Al at low phosphate conditions. Our observations suggest that NPC4 plays a role in both early and long-term responses to Al stress.
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