Evidence map›Paper›PMID 25762771›Full record

ArticleJournal of clinical microbiology2015

An in-house assay is superior to Sepsityper for direct matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry identification of yeast species in blood cultures.

Marie Bidart, Isabelle Bonnet, Aurélie Hennebique, Zine Eddine Kherraf, Hervé Pelloux, François Berger, Muriel Cornet, Sébastien Bailly, Danièle Maubon

Abstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Performance of Short-Term Culture and Direct MALDI-TOF MS for Identification of Candida Species From Blood Cultures.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Multicenter Evaluation of Rapid BACproDiagnostics (Basel, Switzerland) · 2021
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review of the impact of MALDI-TOF MS in public health and hospital hygiene, 2018.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marie BidartUF Clinatec, Pôle Recherche, CHU de Grenoble, Grenoble, France.
Isabelle BonnetLaboratoire de Parasitologie-Mycologie, Institut de Biologie et de Pathologie, CHU de Grenoble, Grenoble, France.
Aurélie HennebiqueLaboratoire de Parasitologie-Mycologie, Institut de Biologie et de Pathologie, CHU de Grenoble, Grenoble, France.
Zine Eddine KherrafLaboratoire de Parasitologie-Mycologie, Institut de Biologie et de Pathologie, CHU de Grenoble, Grenoble, France.
Hervé PellouxLaboratoire de Parasitologie-Mycologie, Institut de Biologie et de Pathologie, CHU de Grenoble, Grenoble, France.
François BergerUF Clinatec, Pôle Recherche, CHU de Grenoble, Grenoble, France.
Muriel CornetLaboratoire de Parasitologie-Mycologie, Institut de Biologie et de Pathologie, CHU de Grenoble, Grenoble, France Laboratoire TIMC-IMAG-TheREx, UMR 5525 CNRS-UJF, Université Grenoble Alpes, Grenoble, France.
Sébastien BaillyLaboratoire de Parasitologie-Mycologie, Institut de Biologie et de Pathologie, CHU de Grenoble, Grenoble, France U823, Grenoble Alpes University, Grenoble, France UMR 1137-IAME Team 5-DeSCID, Inserm/Paris Diderot, Sorbonne Paris Cité University, Paris, France.
Danièle MaubonLaboratoire de Parasitologie-Mycologie, Institut de Biologie et de Pathologie, CHU de Grenoble, Grenoble, France Laboratoire TIMC-IMAG-TheREx, UMR 5525 CNRS-UJF, Université Grenoble Alpes, Grenoble, France dmaubon@chu-grenoble.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We developed an in-house assay for the direct identification, by matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry, of yeasts in blood culture. Sixty-one representative strains from 12 species were analyzed in spiked blood cultures. Our assay accurately identified 95 of 107 (88.8%) positive blood cultures and outperformed the commercial Sepsityper kit (81.7% identification).

Indexed as

BloodFungemiaHumansMicrobiological TechniquesSensitivity and SpecificitySpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationYeasts

Identifiers

PMID25762771
PMCPMC4400771

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.