Evidence map›Paper›PMID 25762768›Full record

ArticleJournal of clinical microbiology2015

A novel technique for detecting antibiotic-resistant typhoid from rapid diagnostic tests.

Caoimhe Nic Fhogartaigh, David A B Dance, Viengmon Davong, Pisey Tann, Rattanaphone Phetsouvanh, Paul Turner, Sabine Dittrich, Paul N Newton

Abstract readEvaluation StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Typhoid in Laos: An 18-Year Perspective.The American journal of tropical medicine and hygiene · 2020
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Caoimhe Nic FhogartaighLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Vientiane, Lao PDR Public Health England, London, England, United Kingdom.
David A B DanceLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Vientiane, Lao PDR Public Health England, London, England, United Kingdom Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, Old Road Campus, University of Oxford, Oxford, England.
Viengmon DavongLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Vientiane, Lao PDR.
Pisey TannCambodia-Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, Cambodia.
Rattanaphone PhetsouvanhLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Vientiane, Lao PDR.
Paul TurnerCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, Old Road Campus, University of Oxford, Oxford, England Cambodia-Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, Cambodia.
Sabine DittrichLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Vientiane, Lao PDR Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, Old Road Campus, University of Oxford, Oxford, England sabine@tropmedres.ac.
Paul N NewtonLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Vientiane, Lao PDR Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, Old Road Campus, University of Oxford, Oxford, England.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Fluoroquinolone-resistant typhoid is increasing. An antigen-detecting rapid diagnostic test (RDT) can rapidly diagnose typhoid from blood cultures. A simple, inexpensive molecular technique performed with DNA from positive RDTs accurately identified gyrA mutations consistent with phenotypic susceptibility testing results. Field diagnosis combined with centralized molecular resistance testing could improve typhoid management and surveillance in low-resource settings.

Indexed as

Drug Resistance, BacterialAdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsBacteriological TechniquesChildChild, PreschoolDiagnostic Tests, RoutineDNA, BacterialDNA GyraseFemaleFluoroquinolonesHumansInfantAnti-Bacterial AgentsDNA, BacterialDNA GyraseFluoroquinolones

Identifiers

PMID25762768
PMCPMC4400746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.