Evidence map›Paper›PMID 25762651›Full record

Trial reportJournal of psychopharmacology (Oxford, England)2015

The role of distress intolerance for panic and nicotine withdrawal symptoms during a biological challenge.

Samantha G Farris, Michael J Zvolensky, Michael W Otto, Teresa M Leyro

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of psychopharmacology (Oxford, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Effects of behavioral interventions on stress reactivity in adults with substance use disorders.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2024
    Trial
  2. Trial
  3. Trial
  4. Trial
  5. Distress intolerance during smoking cessation treatment.Behaviour research and therapy · 2016
    Trial
  6. Article
  7. Behavioral strategies to reduce stress reactivity in opioid use disorder: Study design.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2020
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Distress Intolerance and Smoking Topography in the Context of a Biological Challenge.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Acute effects of cannabis on breath-holding duration.Experimental and clinical psychopharmacology · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samantha G FarrisDepartment of Psychology, University of Houston, Houston, TX, USA sgfarris@uh.edu.
Michael J ZvolenskyDepartment of Psychology, University of Houston, Houston, TX, USA Department of Behavioral Science, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Michael W OttoDepartment of Psychology, Boston University, Boston, MA, USA.
Teresa M LeyroDepartment of Psychology, Rutgers - The State University of New Jersey, New Brunswick, NJ, USA.

Funding

Panic Disorder and Nicotine WithdrawalF31DA024919 · NIDA · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI LEYRO, TERESA MARIA · 2008 to 2010
$104k
Panic-Relevant Sensations and Smoking MotivationF31DA035564 · NIDA · UNIVERSITY OF HOUSTON · PI FARRIS, SAMANTHA GWEN · 2013 to 2015
$101k
NIDA NIH HHS F31 DA024919NIDA NIH HHS F31-DA024919-03NIDA NIH HHS F31 DA035564NIDA NIH HHS F31-DA035564-02NIDA NIH HHS L30 DA036181
6 · The paper itself

Abstract

backgroundDistress intolerance is linked to the maintenance of panic disorder and cigarette smoking, and may underlie both problems.

methodSmokers (n = 54; 40.7% panic disorder) were recruited for an experimental study; half were randomly assigned to 12-hour nicotine deprivation and half smoked as usual. The current investigation consisted of secondary, exploratory analyses from this larger experimental study. Four distress intolerance indices were examined as predictors of anxious responding to an emotional elicitation task (10% carbon dioxide (CO2)-enriched air challenge); anxious responding was in turn examined as a predictor of post-challenge panic and nicotine withdrawal symptoms.

resultsThe Distress Tolerance Scale (DTS) was significantly negatively associated with anxious responding to the challenge (β = -0.41, p = 0.017). The DTS was negatively associated with post-challenge increases nicotine withdrawal symptoms indirectly through the effect of anxious responding to the challenge (b = -0.485, CI95% (-1.095, -0.033)). This same indirect effect was found for post-challenge severity of panic symptoms (b = -0.515, CI95% (-0.888, -0.208)). The DTS was directly predictive of post-challenge increases nicotine withdrawal symptoms, in the opposite direction (β = 0.37, p = 0.009), but not panic symptom severity.

conclusionsAnxious responding in response to stressful experiences may explain the impact of perceived distress intolerance on panic and nicotine withdrawal symptom expression.

Indexed as

AdolescentAdultAnxietyCarbon DioxideFemaleHumansMalePanicPanic DisorderSeverity of Illness IndexSmokingStress, PsychologicalSubstance Withdrawal SyndromeYoung AdultCarbon Dioxidebiological challengeCO2Distress intolerancepanic disorderwithdrawal

Identifiers

PMID25762651
PMCPMC6561481

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.