ArticleG3 (Bethesda, Md.)2015
Multiple Phosphatases Regulate Carbon Source-Dependent Germination and Primary Metabolism in Aspergillus nidulans.
Article in G3 (Bethesda, Md.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Frontiers in fungal phosphatases: molecular diversity, regulatory mechanisms, analytical methodologies, ecological significance, and prospects for sustainable utilization.Frontiers in bioengineering and biotechnology · 2026Review
- Article
- MAPkinases regulate secondary metabolism, sexual development and light dependent cellulase regulation in Trichoderma reesei.Scientific reports · 2023Article
- Effect of Water Activity on Conidia Germination inMicroorganisms · 2022Article
- Novel Treatment Approach for Aspergilloses by Targeting Germination.Journal of fungi (Basel, Switzerland) · 2022Review
- Fungal phytopathogen modulates plant and insect responses to promote its dissemination.The ISME journal · 2021Article
- Article
- HJournal of fungi (Basel, Switzerland) · 2021Article
- The High Osmolarity Glycerol Mitogen-Activated Protein Kinase regulates glucose catabolite repression in filamentous fungi.PLoS genetics · 2020Article
- The Kinase USK1 Regulates Cellulase Gene Expression and Secondary Metabolite Biosynthesis inFrontiers in microbiology · 2020Article
- Protein phosphatases regulate growth, development, cellulases and secondary metabolism in Trichoderma reesei.Scientific reports · 2019Article
- TheG3 (Bethesda, Md.) · 2018Article
- The low affinity glucose transporter HxtB is also involved in glucose signalling and metabolism in Aspergillus nidulans.Scientific reports · 2017Article
- Metabolic activity in dormant conidia of Aspergillus niger and developmental changes during conidial outgrowth.Fungal genetics and biology : FG & B · 2016Article
- Systematic Global Analysis of Genes Encoding Protein Phosphatases in Aspergillus fumigatus.G3 (Bethesda, Md.) · 2015Article
- Aspergillus nidulans protein kinase A plays an important role in cellulase production.Biotechnology for biofuels · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aspergillus nidulans is an important mold and a model system for the study of fungal cell biology. In addition, invasive A. nidulans pulmonary infections are common in humans with chronic granulomatous disease. The morphological and biochemical transition from dormant conidia into active, growing, filamentous hyphae requires the coordination of numerous biosynthetic, developmental, and metabolic processes. The present study exhibited the diversity of roles performed by seven phosphatases in regulating cell cycle, development, and metabolism in response to glucose and alternative carbon sources. The identified phosphatases highlighted the importance of several signaling pathways regulating filamentous growth, the action of the pyruvate dehydrogenase complex as a metabolic switch controlling carbon usage, and the identification of the key function performed by the α-ketoglutarate dehydrogenase during germination. These novel insights into the fundamental roles of numerous phosphatases in germination and carbon sensing have provided new avenues of research into the identification of inhibitors of fungal germination, with implications for the food, feed, and pharmaceutical industries.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.