ArticleIn vitro cellular & developmental biology. Animal2015
Transcriptome analysis reveals the potential mechanism of the albino skin development in pufferfish Takifugu obscurus.
Article in In vitro cellular & developmental biology. Animal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 5 citations in OpenAlex.
- Single-Nucleus Transcriptional Profiling Revealed Cell Diversity and Albino Mutation Mechanism in the Skin ofInternational journal of molecular sciences · 2026Article
- Analysis of yellow mutant rainbow trout transcriptomes at different developmental stages reveals dynamic regulation of skin pigmentation genes.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Our aim was to explore the potential mechanism underlying albino in Takifugu obscurus. The transcriptome sequencing of the skin samples from normal T. obscurus and albino ones was conducted in this paper. The differentially expressed genes (DEGs) in albino fish compared with controls were assayed. The gene ontology (GO) and Kyoto encyclopedia of genes and genomes (KEGG) pathway analysis were performed to explore the differentially expressed gene (DEG)-related functions and pathways. A total of 32 genes were found to be differentially expressed, including eight upregulated ones and 24 downregulated ones. Five GO terms were significantly enriched such as hemoglobin complex and oxygen transporter activity. The significantly enriched pathways contained linoleic acid metabolism and arachidonic acid metabolism. Hemoglobin complex, linoleic, and arachidonic acid metabolism may dysregulated in albino fugu. Dietary control of the linoleic acid and arachidonic acid may be an effective management for mediating albino in T. obscurus.
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