Evidence map›Paper›PMID 25761540›Full record

ArticleIntensive care medicine2015

Safety and feasibility of a strategy of early central venous catheter insertion in a deployed UK military Ebola virus disease treatment unit.

P S C Rees, L E M Lamb, T C Nicholson-Roberts, C N Ardley, M S Bailey, D E Hinsley, T E Fletcher, S J Dickson

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Intensive care medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Bleeding Risk of Central Venous Catheterization in Adults: A Systematic Review and Meta-analysis.TH open : companion journal to thrombosis and haemostasis · 2025
    Review
  3. Critical care and pandemic preparedness and response.British journal of anaesthesia · 2023
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Ebola virus disease and critical illness.Critical care (London, England) · 2016
    Review
  10. Article
  11. Working on the front line.Clinical medicine (London, England) · 2015
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

P S C ReesAcademic Department of Military Medicine, Royal Centre for Defence Medicine (Academia and Research), Medical Directorate, Joint Medical Command, ICT Centre, Birmingham Research Park, B15 2SQ, Birmingham, UK, drpscrees@aol.com.
L E M Lamb
T C Nicholson-Roberts
C N Ardley
M S Bailey
D E Hinsley
T E Fletcher
S J Dickson
Birmingham Research Park · GBSt Bartholomew's Hospital · GB

Funding

Wellcome Trust 100890
6 · The paper itself

Abstract

purposeEarly central venous catheter (CVC) insertion in Ebola virus disease (EVD) is a novel approach and has not previously been described. This report delineates the safety, feasibility and clinical implications of early CVC insertion as the optimum means of vascular access in patients with EVD, in the setting of a deployed military Ebola virus disease treatment unit in Sierra Leone.

methodsIn the gastrointestinal phase of EVD, a 7-French 20-cm triple-lumen CVC was inserted using aseptic technique. Data were collected prospectively on all cases to include baseline and subsequent blood test variables, insertion site and technique, and complications associated with CVC placement.

resultsTwenty-three patients underwent CVC insertion as follows: subclavian, 21 (88 %); internal jugular, 2 (8 %); axillary, 1 (4 %). The mean duration of CVC placement was 5 days. There were no significant procedure-related adverse events. Despite coagulopathy being present in 75 % of cases, CVC insertion was safe, and there was only 1 case of significant catheter site bleeding. A total of 152 needle venepunctures were avoided owing to the presence of a CVC, a mean of 7 (±3.8) per case over the average stay.

conclusionThe early use of CVCs in Ebola virus disease is safe, effective and facilitates patient care. It should be considered a feasible additional route of venous access, where physician expertise and resources allow.

Indexed as

AdultAntiviral AgentsCatheterization, Central VenousCentral Venous CathetersFemaleHemorrhagic Fever, EbolaHumansMaleMiddle AgedMilitary MedicineMilitary PersonnelPatient SafetySierra LeoneTime FactorsUnited KingdomYoung AdultAntiviral Agents

Identifiers

PMID25761540
OpenAlexW1973059975

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.