ArticleActa crystallographica. Section F, Structural biology communications2015
Origin and use of crystallization phase diagrams.
Article in Acta crystallographica. Section F, Structural biology communications, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Automated microbatch-under-oil phase diagrams to rationalize serial crystallography sample preparation.IUCrJ · 2026Article
- Crystal phase formation in crowded lysozyme solutions.RSC advances · 2026Article
- Biological Systems Depend on Communication Over Distances: A Review of the Fundamental Mechanisms, Associated challenges, and the Potential Effect of the Constrained Disorder Principle.Acta biotheoretica · 2026Review
- The Starting Point for Biomolecular Crystallisation.Advances in biochemical engineering/biotechnology · 2026Review
- Phase Diagrams as a DOE Tool in Biomolecular Crystallization.Advances in biochemical engineering/biotechnology · 2026Review
- Homogeneous batch micro-crystallization of proteins from ammonium sulfate.Acta crystallographica. Section D, Structural biology · 2021Article
- Semi-empirical model to estimate ideal conditions for the growth of large protein crystals.Acta crystallographica. Section D, Structural biology · 2020Article
- Successful sample preparation for serial crystallography experiments.Journal of applied crystallography · 2019Article
- Expression, Purification, Crystallization, and Enzyme Assays of Fumarylacetoacetate Hydrolase Domain-Containing Proteins.Journal of visualized experiments : JoVE · 2019Article
- Article
- Optimizing Associative Experimental Design for Protein Crystallization Screening.IEEE transactions on nanobioscience · 2016Article
- Protein stability: a crystallographer's perspective.Acta crystallographica. Section F, Structural biology communications · 2016Review
- Large-volume protein crystal growth for neutron macromolecular crystallography.Acta crystallographica. Section F, Structural biology communications · 2015Article
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Abstract
Crystallization phase diagrams are frequently used to conceptualize the phase relations and also the processes taking place during the crystallization of macromolecules. While a great deal of freedom is given in crystallization phase diagrams owing to a lack of specific knowledge about the actual phase boundaries and phase equilibria, crucial fundamental features of phase diagrams can be derived from thermodynamic first principles. Consequently, there are limits to what can be reasonably displayed in a phase diagram, and imagination may start to conflict with thermodynamic realities. Here, the commonly used `crystallization phase diagrams' are derived from thermodynamic excess properties and their limitations and appropriate use is discussed.
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