ArticlePloS one2015
RNA-dependent RNA polymerase (NIb) of the potyviruses is an avirulence factor for the broad-spectrum resistance gene Pvr4 in Capsicum annuum cv. CM334.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 47 citations in OpenAlex.
- Molecular Identification and Pathogenicity of a Chilli Veinal Mottle Virus Isolate from Sichuan, China.International journal of molecular sciences · 2026Article
- Fine mapping of the Chilli veinal mottle virus resistance 4 (cvr4) gene in pepper (Capsicum annuum L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Molecular and genomic insights into viral resistance inFrontiers in plant science · 2025Review
- Advances in understanding the interaction betweenPlant signaling & behavior · 2024Review
- A Novel Cryptic Virus Isolated fromPathogens (Basel, Switzerland) · 2024Article
- Current knowledge and breeding strategies for management of aphid-transmitted viruses of pepper (Frontiers in plant science · 2024Review
- The Hypersensitive Response to Plant Viruses.Viruses · 2023Review
- Signaling and Resistosome Formation in Plant Innate Immunity to Viruses: Is There a Common Mechanism of Antiviral Resistance Conserved across Kingdoms?International journal of molecular sciences · 2023Review
- A plant RNA virus inhibits NPR1 sumoylation and subverts NPR1-mediated plant immunity.Nature communications · 2023Article
- Thirty years of resistance: Zig-zag through the plant immune system.The Plant cell · 2022Review
- Article
- Identification of viral genes involved in pepper mottle virus replication and symptom development inFrontiers in plant science · 2022Article
- Review
- Resistance induction based on the understanding of molecular interactions between plant viruses and host plants.Virology journal · 2021Review
- Review
- Genome-wide functional analysis of hot pepper immune receptors reveals an autonomous NLR clade in seed plants.The New phytologist · 2021Article
- Extreme Resistance to Viruses in Potato and Soybean.Frontiers in plant science · 2021Review
- The inhibitory effects of metabolites from Bacillus pumilus on potato virus Y and the induction of early response genes in Nicotiana tabacum.AMB Express · 2020Article
- Overview of Biotic Stresses in Pepper (International journal of molecular sciences · 2020Review
- Plant Molecular Responses to Potato Virus Y: A Continuum of Outcomes from Sensitivity and Tolerance to Resistance.Viruses · 2020Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Potyviruses are one of the most destructive viral pathogens of Solanaceae plants. In Capsicum annuum landrace CM334, a broad-spectrum gene, Pvr4 is known to be involved in resistance against multiple potyviruses, including Pepper mottle virus (PepMoV), Pepper severe mosaic virus (PepSMV), and Potato virus Y (PVY). However, a potyvirus avirulence factor against Pvr4 has not been identified. To identify the avirulence factor corresponding to Pvr4 in potyviruses, we performed Agrobacterium-mediated transient expressions of potyvirus protein coding regions in potyvirus-resistant (Pvr4) and -susceptible (pvr4) pepper plants. Hypersensitive response (HR) was observed only when a RNA-dependent RNA polymerase (NIb) of PepMoV, PepSMV, or PVY was expressed in Pvr4-bearing pepper leaves in a genotype-specific manner. In contrast, HR was not observed when the NIb of Tobacco etch virus (TEV), a virulent potyvirus, was expressed in Pvr4-bearing pepper leaves. Our results clearly demonstrate that NIbs of PepMoV, PepSMV, and PVY serve as avirulence factors for Pvr4 in pepper plants.
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