Evidence map›Paper›PMID 25760263›Full record

ArticleJournal of applied oral science : revista FOB

TiF4 and NaF varnishes as anti-erosive agents on enamel and dentin erosion progression in vitro.

Livia Picchi Comar, Cristiane de Almeida Baldini Cardoso, Senda Charone, Larissa Tercilia Grizzo, Marília Afonso Rabelo Buzalaf, Ana Carolina Magalhães

Abstract readEvaluation Study
In one paragraph

Article in Journal of applied oral science : revista FOB. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Efficacy and safety of TiFScientific reports · 2024
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  15. The effect of COLasers in medical science · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Livia Picchi ComarDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.
Cristiane de Almeida Baldini CardosoDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.
Senda CharoneDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.
Larissa Tercilia GrizzoDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.
Marília Afonso Rabelo BuzalafDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.
Ana Carolina MagalhãesDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study assessed the effect of fluoride varnishes on the progression of tooth erosion in vitro. MATERIAL AND

methodsForty-eight enamel and 60 root dentin samples were previously demineralized (0.1% citric acid, pH 2.5, 30 min), leading to a baseline and erosive wear of 12.9 and 11.4 µm, respectively. The samples were randomly treated (6 h) with a 4% TiF4 varnish (2.45%F-, pH 1.0), a 5.42% NaF varnish (2.45%F-, pH 5.0), a placebo varnish and no varnish (control). The samples were then subjected to erosive pH cycles (4x90 s/day in 0.1% citric acid, intercalated with artificial saliva) for 5 days. The increment of the erosive tooth wear was calculated. In the case of dentin, this final measurement was done with and without the demineralized organic matrix (DOM). Enamel and dentin data were analyzed using ANOVA/Tukey's and Kruskal-Wallis/Dunn tests, respectively (p<0.05).

resultsThe TiF4 (mean±s.d: 1.5±1.1 µm) and NaF (2.1±1.7 µm) varnishes significantly reduced enamel wear progression compared to the placebo varnish (3.9±1.1 µm) and control (4.5±0.9 µm). The same differences were found for dentin in the presence and absence of the DOM, respectively: TiF4 (average: 0.97/1.87 µm), NaF (1.03/2.13 µm), placebo varnish (3.53/4.47 µm) and control (3.53/4.36 µm).

conclusionThe TiF4 and NaF varnishes were equally effective in reducing the progression of tooth erosion in vitro.

Indexed as

AnimalsCariostatic AgentsCattleDental EnamelDentinFluoridesFluorides, TopicalHydrogen-Ion ConcentrationRandom AllocationReproducibility of ResultsSodium FluorideTime FactorsTitaniumTooth DemineralizationTooth ErosionTreatment OutcomeCariostatic AgentsFluoridesFluorides, TopicalSodium FluorideTitaniumtitanium tetrafluoride

Identifiers

PMID25760263
PMCPMC4349114

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.