ReviewJournal of immunology research2015
Intestinal microbiota as modulators of the immune system and neuroimmune system: impact on the host health and homeostasis.
Review in Journal of immunology research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Therapy with probiotics and synbiotics for polycystic ovarian syndrome: a systematic review and meta-analysis.European journal of nutrition · 2020Pooled it
- Intestinal Epithelial-Protective Effects ofJournal of microbiology and biotechnology · 2026Article
- Sheep-derived probiotics alleviate weaning-induced oxidative stress in lambs via the gut-liver axis.NPJ biofilms and microbiomes · 2026Article
- Decoding the gut microbiota-mitochondrial-inflammasome axis in cardiovascular disease.Molecular and cellular biochemistry · 2026Review
- Early antimicrobial regimen shapes gut microbiota and health trajectories in pigs: a longitudinal study from weaning to finishing.Animal microbiome · 2025Article
- A Novel Dietary Index for Gut Microbiota (DI-GM) is Associated With Inflammation, Mental Health, and Tumor Biomarkers in Adults: A Cross-Sectional Study.Food science & nutrition · 2025Article
- Diabetic wounds and short-chain fatty acids.Journal of diabetes and metabolic disorders · 2025Review
- Associations and Related Mechanisms of Attention-Deficit Hyperactivity Disorder and Allergic Rhinitis in Children.Psychiatry and clinical psychopharmacology · 2025Review
- Gut-X axis.iMeta · 2025Review
- Gestational diabetes mellitus alters neonatal gut microbiota and increases infection susceptibility.Frontiers in microbiology · 2025Article
- The gut-lung axis: effects and mechanisms of gut microbiota on pulmonary diseases.Frontiers in immunology · 2025Review
- Unraveling the Gut Microbiota: Implications for Precision Nutrition and Personalized Medicine.Nutrients · 2024Review
- Review
- Understanding the Role of Female Genital Tract Microbiome in Recurrent Implantation Failure.Journal of clinical medicine · 2024Review
- Synbiotic ofJournal of microbiology and biotechnology · 2024Article
- Mouse diet and vendor impact microbiome perturbation and recovery from early-life pulses of amoxicillin.Frontiers in microbiomes · 2024Article
- Gestational diabetes mellitus: genetic factors, epigenetic alterations, and microbial composition.Acta diabetologica · 2024Review
- Therapeutic role of gut microbiota in lung injury-related cognitive impairment.Frontiers in nutrition · 2024Review
- A review of the pathogenesis of epilepsy based on the microbiota-gut-brain-axis theory.Frontiers in molecular neuroscience · 2024Review
- Canine diffuse large b-cell lymphoma downregulates the activity of CD8 + T-cells through tumor-derived extracellular vesicles.Cancer cell international · 2023Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many immune-based intestinal disorders, such as ulcerative colitis and Crohn's disease, as well as other illnesses, may have the intestines as an initial cause or aggravator in the development of diseases, even apparently not correlating directly to the intestine. Diabetes, obesity, multiple sclerosis, depression, and anxiety are examples of other illnesses discussed in the literature. In parallel, importance of the gut microbiota in intestinal homeostasis and immunologic conflict between tolerance towards commensal microorganisms and combat of pathogens is well known. Recent researches show that the immune system, when altered by the gut microbiota, influences the state in which these diseases are presented in the patient directly and indirectly. At the present moment, a considerable number of investigations about this subject have been performed and published. However, due to difficulties on correlating information, several speculations and hypotheses are generated. Thus, the present review aims at bringing together how these interactions work-gut microbiota, immune system, and their influence in the neuroimmune system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.