Evidence map›Paper›PMID 25759821›Full record

ArticleBioMed research international2015

Evaluation of deformable image registration methods for dose monitoring in head and neck radiotherapy.

Bastien Rigaud, Antoine Simon, Joël Castelli, Maxime Gobeli, Juan-David Ospina Arango, Guillaume Cazoulat, Olivier Henry, Pascal Haigron, Renaud De Crevoisier

Abstract read
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. A density assignment method for dose monitoring in head-and-neck radiotherapy.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bastien RigaudUniversité de Rennes 1, LTSI, Campus de Beaulieu, 35000 Rennes, France ; INSERM, U1099, Campus de Beaulieu, 35000 Rennes, France.
Antoine SimonUniversité de Rennes 1, LTSI, Campus de Beaulieu, 35000 Rennes, France ; INSERM, U1099, Campus de Beaulieu, 35000 Rennes, France.
Joël CastelliUniversité de Rennes 1, LTSI, Campus de Beaulieu, 35000 Rennes, France ; INSERM, U1099, Campus de Beaulieu, 35000 Rennes, France ; Centre Eugene Marquis, Radiotherapy Department, 35000 Rennes, France.
Maxime GobeliCentre Eugene Marquis, Radiotherapy Department, 35000 Rennes, France.
Juan-David Ospina ArangoUniversité de Rennes 1, LTSI, Campus de Beaulieu, 35000 Rennes, France ; INSERM, U1099, Campus de Beaulieu, 35000 Rennes, France.
Guillaume CazoulatUniversité de Rennes 1, LTSI, Campus de Beaulieu, 35000 Rennes, France ; INSERM, U1099, Campus de Beaulieu, 35000 Rennes, France.
Olivier HenryCentre Eugene Marquis, Radiotherapy Department, 35000 Rennes, France.
Pascal HaigronUniversité de Rennes 1, LTSI, Campus de Beaulieu, 35000 Rennes, France ; INSERM, U1099, Campus de Beaulieu, 35000 Rennes, France.
Renaud De CrevoisierUniversité de Rennes 1, LTSI, Campus de Beaulieu, 35000 Rennes, France ; INSERM, U1099, Campus de Beaulieu, 35000 Rennes, France ; Centre Eugene Marquis, Radiotherapy Department, 35000 Rennes, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the context of head and neck cancer (HNC) adaptive radiation therapy (ART), the two purposes of the study were to compare the performance of multiple deformable image registration (DIR) methods and to quantify their impact for dose accumulation, in healthy structures. Fifteen HNC patients had a planning computed tomography (CT0) and weekly CTs during the 7 weeks of intensity-modulated radiation therapy (IMRT). Ten DIR approaches using different registration methods (demons or B-spline free form deformation (FFD)), preprocessing, and similarity metrics were tested. Two observers identified 14 landmarks (LM) on each CT-scan to compute LM registration error. The cumulated doses estimated by each method were compared. The two most effective DIR methods were the demons and the FFD, with both the mutual information (MI) metric and the filtered CTs. The corresponding LM registration accuracy (precision) was 2.44 mm (1.30 mm) and 2.54 mm (1.33 mm), respectively. The corresponding LM estimated cumulated dose accuracy (dose precision) was 0.85 Gy (0.93 Gy) and 0.88 Gy (0.95 Gy), respectively. The mean uncertainty (difference between maximal and minimal dose considering all the 10 methods) to estimate the cumulated mean dose to the parotid gland (PG) was 4.03 Gy (SD = 2.27 Gy, range: 1.06-8.91 Gy).

Indexed as

AgedAged, 80 and overHead and Neck NeoplasmsHumansMiddle AgedRadiation DosageRadiation MonitoringRadiotherapy, Intensity-ModulatedTomography, X-Ray Computed

Identifiers

PMID25759821
PMCPMC4339705

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.