ArticleBalkan medical journal2015
Effect of obesity on left ventricular longitudinal myocardial strain by speckle tracking echocardiography in children and adolescents.
Article in Balkan medical journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Obesity and Left Ventricular Mechanics in Children and Adolescents: A Systematic Review and Meta-Analysis.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025Pooled it
- The effect of overweight/obesity on diastolic function in children and adolescents: A meta-analysis.Clinical obesity · 2021Pooled it
- Natural history of myocardial deformation in children, adolescents, and young adults exposed to anthracyclines: Systematic review and meta-analysis.Echocardiography (Mount Kisco, N.Y.) · 2018Pooled it
- Impact of weight loss on cardiovascular function in adolescents and young adults with overweight/ obesity and intellectual and developmental disabilities.Disability and health journal · 2026Article
- Targeting Myocardial Mechanics in Children and Adolescents with Obesity and Non-Elevated Blood Pressure: A Meta-Regression Study.Diseases (Basel, Switzerland) · 2025Review
- The Impact of BMI on Ventricular Function Recovery in Children After Pediatric Inflammatory Multisystem Syndrome (PIMS-TS).Journal of clinical medicine · 2024Article
- Obesity: the perfect storm for heart failure.ESC heart failure · 2024Review
- Impact of obesity on echocardiographic parameters in individuals free of CVD using anthropometric measurements.The British journal of cardiology · 2024Article
- Evaluation of subclinical left ventricular systolic dysfunction in obese patients by global myocardial work.Diabetology & metabolic syndrome · 2023Article
- Association of abdominal adiposity, hepatic shear stiffness with subclinical left-ventricular remodeling evaluated by magnetic resonance in adults free of overt cardiovascular diseases: a prospective study.Cardiovascular diabetology · 2023Article
- Establishment of Myocardial Strain Measurement Data in Pediatric Patients Without Structural Heart Disease: A Single Center Study.Pediatric cardiology · 2020Article
- Racial differences in myocardial deformation in obese children: Significance of inflammatory state.Nutrition, metabolism, and cardiovascular diseases : NMCD · 2019Article
- Evaluation of subclinical left ventricular dysfunction in overweight people with 3D speckle-tracking echocardiography.Anatolian journal of cardiology · 2019Article
- Preclinical cardiovascular changes in children with obesity: A real-time 3-dimensional speckle tracking imaging study.PloS one · 2018Article
- Factors affecting the left atrial diameter.Anatolian journal of cardiology · 2017Article
- Subclinical Impairment of Left Ventricular Function assessed by Speckle Tracking in Type 2 Diabetic Obese and Non-Obese Patients: Case Control Study.Journal of cardiovascular echographyArticle
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Authors and funding
7 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundImpaired subclinical ventricular function may contribute to the risk of cardiovascular disease in obesity.
aimsThe aim of this study was to determine the influence of obesity on left ventricular (LV) longitudinal myocardial function in normotensive obese children using two-dimensional (2D) speckle tracking echocardiography (STE). STUDY
designCase-control study.
methodsSixty normotensive obese children aged 10-16 years (mean age, 13.9±2.3 years) were compared with 50 normal-weight controls. Obese participants had a body mass index (BMI)≥95(th) percentile. Regional strain/strain rate (SR) values were compared with left ventricular (LV) parameters. The correlation was studied by linear regression analysis.
resultsObese subjects exhibited a significantly higher LV end-diastolic diameter, left atrium/aortic diameter ratio, and LV mass/index when compared to controls (p<0.001). Left ventricular ejection fraction and regional systolic myocardial velocities were similar in the obese and control groups. By 2D STE, regional strain of both the septal wall (average strain: -16.0±3.9% vs -21.9±2.4%, p<0.001) and lateral wall (average strain: -15.6±2.3% vs -22.9±3.5%, p<0.001); regional SR of both the septal wall (average SRsys: -0.7±0.22 s(-1) vs -1.3±0.32 s(-1), p<0.001) and lateral wall (average SRsys: -0.67±0.19 s(-1) vs -1.33±0.31 s(-1), p<0.001); regional SRE/A of both the septal wall (average SRE/A: 1.8±0.83 vs. 2.2±0.91, p: 0.004) and lateral wall (average SRE/A: 1.4±0.43 vs. 2.4±1.21, p<0.001); and global strain (-14.6±7.34% vs -20.9±3.24%, p<0.001) were lower in the obese group compared with the controls. These strain imaging parameters appear to be related to the severity of obesity and can contribute to increased BMI. Left ventricular mass was found to be correlated with a decrease in global LV strain.
conclusionOur study showed that childhood obesity is associated with an alteration in the longitudinal LV function. Segmental analysis of the LV can provide subtle markers for the emergence of future obesity-related cardiac disease.
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