ArticleIranian journal of parasitology
Frequency of Toxoplasma gondii in HIV Positive Patients from West of Iran by ELISA and PCR.
Article in Iranian journal of parasitology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.
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Who cites it
28 citing papers in PubMed, 4 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- The Global Prevalence of and Factors Associated with Parasitic Coinfection in People Living with Viruses: A Systematic Review and Meta-Analysis.Pathogens (Basel, Switzerland) · 2025Pooled it
- Human Toxoplasma gondii infection in Nigeria: a systematic review and meta-analysis of data published between 1960 and 2019.BMC public health · 2020Pooled it
- Acute Toxoplasma infection in pregnant women worldwide: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2019Pooled it
- A systematic review and meta-analysis of the prevalence of toxoplasmosis in hemodialysis patients in Iran.Epidemiology and health · 2018Pooled it
- Association of polymorphism of IL-17A, IL-17F, and IL-6 with Toxoplasma gondii infection susceptibility in HIV/AIDS patients in Shiraz, southern Iran.Immunity, inflammation and disease · 2024Article
- Molecular investigation of Toxocara infection from the serum of people living with HIV in Alborz, Iran.BMC infectious diseases · 2023Article
- A serological survey of Toxoplasma gondii in polish pigs from organic farms, other housing systems and in pigs of different age groups.Acta veterinaria Scandinavica · 2022Article
- Seronegative Infection withJournal of clinical medicine · 2022Article
- Seroprevalence Estimates of Latent and AcuteMicroorganisms · 2021Article
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- Development of High Resolution Melting Analysis as a Diagnostic Tool for Molecular Detection ofIranian journal of public health · 2020Article
- Genetic characterization ofParasitology · 2020Article
- Evaluation of a PCR assay for diagnosis of toxoplasmosis in serum and peripheral blood mononuclear cell among HIV/AIDS patients.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2020Article
- Detection ofIranian journal of public health · 2019Article
- Prevalence ofIranian journal of pathology · 2019Article
- Advances in serological, imaging techniques and molecular diagnosis of Toxoplasma gondii infection.Infection · 2018Review
- Anti-International journal of nanomedicine · 2018Article
- Article
- Human infectious diseases and risk of preeclampsia: an updated review of the literature.Infection · 2017Review
- Seroprevalence ofThe Korean journal of parasitology · 2017Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundToxoplasma gondii, the obligate intracellular parasite is life threatening in AIDS patients. Diagnosis of toxoplasmosis is based on serological methods especially increasing of IgM and IgG titers, but finding of parasite or its components (antigenemia) may be beneficial method in order to detection of acute toxoplasmosis in immunocompromised patients.
methodsNinety-four serum samples from HIV positive patients were collected from Sanandaj, Kordistan west of Iran. These patients were lived in Sanandaj of whom 26 were prisoners infected with HIV virus in prison. Toxoplasma gondii antibodies were determined by IgG ELISA. T. gondii antigen was identified by capture-ELISA. PCR was performed on samples with T. gondii antigenemia. CD4+ T cells counts had been determined by flowcytometry and were obtained from records of each patient.
resultsAmong the examined HIV seropositive individuals, 19.1% (18/94) and 5.3% (5/94) were positive for Toxoplasma-IgG and antigenemia, respectively. Besides, one of the samples was positively detected by PCR method. Mean age of participants was 37.9 ± 9.5 year. Prevalence of IgG antibody and antgenemia was higher in age group of 40-50 years old. The Mean of CD4+ T cells counts of participants (total of HIV+ patients, IgG positive patients and patients with antigenemia) was 699.2 ± 345.2, 655.1 ± 237.9 and 620.2 ± 215.1 respectively.
conclusionCapture-ELISA and PCR could confirm the T. gondii acute infection in HIV positive patients. For precise diagnosis of acute toxoplasmosis in HIV positive patient, performance of more studies based on more sensitive types of PCR is suggested.
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Identifiers
25759728PMC4345086W2188856236What OpenQuestion holds
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