ArticleFrontiers in microbiology2015
A comprehensive analysis of the microbial communities of healthy and diseased marine macroalgae and the detection of known and potential bacterial pathogens.
Article in Frontiers in microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Standardized 16S Meta-Analysis Reveals Consistent Host-Associated Patterns in Laminariales Epiphytic Microbiomes.MicrobiologyOpen · 2026Pooled it
- Taxonomy, tissue, and habitat influence mollusk microbial communities.The ISME journal · 2026Pooled it
- Opportunistic diseases in marine eukaryotes: Could Bacteroidota be the next threat to ocean life?Environmental microbiology · 2022Pooled it
- Examining Short Temporal Changes in Intertidal Macroalgal Microbiomes at 'Ewa Beach, O'Ahu, Hawai'i: Some Hosts Varied While Others Remained Stable.Environmental microbiology reports · 2026Article
- Bacterial disease in seaweed aquaculture: pathogen diversity and future solutions.Journal of applied phycology · 2026Review
- Multi-omics analysis reveals the pathobiome-host interactions in the bleaching disease of the seaweed Saccharina japonica.Microbiome · 2025Article
- Advancements in Algal Microbiome Research: A Game-Changer for Climate Resilience and Invasion Success?Microbial ecology · 2025Review
- Article
- Antibacterial Activities and Life Cycle Stages ofMarine drugs · 2023Article
- Shell Disease Syndrome Is Associated with Reduced and Shifted Epibacterial Diversity on the Carapace of the Crustacean Cancer pagurus.Microbiology spectrum · 2022Article
- Bacterial controlled mitigation of dysbiosis in a seaweed disease.The ISME journal · 2022Article
- Seasonal succession of bacterial communities in culturedOpen life sciences · 2022Article
- Impacts of environmental stress on resistance and resilience of algal-associated bacterial communities.Ecology and evolution · 2021Article
- Structural and Functional Impacts of Microbiota onMicroorganisms · 2021Article
- Bacterial Communities Associated With Healthy and Bleached Crustose Coralline AlgaFrontiers in microbiology · 2021Article
- Diversity and Dynamics of Seaweed Associated Microbial Communities Inhabiting the Lagoon of Venice.Microorganisms · 2020Article
- Triclosan changes community composition and selects for specific bacterial taxa in marine periphyton biofilms in low nanomolar concentrations.Ecotoxicology (London, England) · 2020Article
- Impacts of dibenzopyrenes on bacterial community isolated from Gulf of Mexico sediment.MicrobiologyOpen · 2020Article
- Review
- High-throughput sequencing revealed differences of microbial community structure and diversity between healthy and diseased Caulerpa lentillifera.BMC microbiology · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microorganisms are increasingly being recognized as the causative agents in the diseases of marine higher organisms, such as corals, sponges, and macroalgae. Delisea pulchra is a common, temperate red macroalga, which suffers from a bleaching disease. Two bacterial strains, Nautella italica R11 and Phaeobacter gallaeciensis LSS9, have been shown in vitro to cause bleaching symptoms, but previous work has failed to detect them during a natural bleaching event. To provide a link between in vitro observations and natural occurrences of the disease, we employ here deep-sequencing of the 16S rRNA gene to comprehensively analyze the community composition of healthy and diseased D. pulchra samples from two separate locations. We observed operational taxonomic units (OTUs) with 100% identity and coverage to the 16S RNA gene sequence of both in vitro pathogens, but only the OTU with similarity to strain LSS9 showed a statistically significant higher abundance in diseased samples. Our analysis also reveals the existence of other bacterial groups within the families Rhodobacteraceae and Flavobacteriaceae that strongly contribute to difference between diseased and healthy samples and thus these groups potentially contain novel macroalgal pathogens and/or saprophytes. Together our results provide evidence for the ecological relevance of one kind of in vitro pathogen, but also highlight the possibility that multiple opportunistic pathogens are involved in the bleaching disease of D. pulchra.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.