Trial reportInternational journal of chronic obstructive pulmonary disease2015
Self-reported sleep quality and acute exacerbations of chronic obstructive pulmonary disease.
Trial report in International journal of chronic obstructive pulmonary disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- What is the most effective non-pharmacological treatment for poor sleep quality in Chronic obstructive pulmonary disease patients? a systematic review.Sleep & breathing = Schlaf & Atmung · 2026Pooled it
- Physical activity, sedentary behaviour and sleep in COPD guidelines: A systematic review.Chronic respiratory disease · 2017Pooled it
- Dose-response to inhaled glycopyrrolate delivered with a novel Co-Suspension™ Delivery Technology metered dose inhaler (MDI) in patients with moderate-to-severe COPD.Respiratory research · 2016Trial
- Machine learning model based on survey assessment of sleep quality in chronic obstructive pulmonary disease patients.PloS one · 2025Article
- Examining the Effect of Sleep Hygiene Education Given to Nursing Students on Sleep Quality.La Medicina del lavoro · 2024Article
- Circadian Disruption in Night Shift Work and Its Association with Chronic Pulmonary Diseases.Advanced biology · 2023Review
- Poor sleep quality, COPD severity and survival according to CASIS and Pittsburgh questionnaires.Scientific reports · 2023Article
- Insomnia in chronic obstructive pulmonary disease and associations with healthcare utilization and costs.Respiratory research · 2023Article
- Mental health and sleep quality among patients with asthma and COPD.Frontiers in medicine · 2023Article
- Prevalence and Predictors of Sleep Disturbance, Anxiety and Depression among Patients with Chronic Respiratory Diseases.International journal of environmental research and public health · 2022Article
- Risk of COPD exacerbation is increased by poor sleep quality and modified by social adversity.Sleep · 2022Observational
- Compensatory responses to increased mechanical abnormalities in COPD during sleep.European journal of applied physiology · 2022Article
- Long-Term Domiciliary Noninvasive Ventilation for COPD.Respiratory care · 2021Article
- Sleep quality and its association with health-related quality of life of patients on lung transplantation waitlist in Japan.Sleep & breathing = Schlaf & Atmung · 2021Article
- The Effect of Symptom Clusters and Sleep Disorder on Quality of Life among Patients with Chronic Obstructive Pulmonary Disease.Journal of healthcare engineering · 2021Article
- Tossing and turning: association of sleep quantity-quality with physical activity in COPD.ERJ open research · 2020Article
- Evaluation of the Vibe Actigraph in Patients With Chronic Obstructive Pulmonary Disease: A Pilot Study.IEEE journal of translational engineering in health and medicine · 2020Article
- Impaired Sleep Quality in COPD Is Associated With Exacerbations: The CanCOLD Cohort Study.Chest · 2019Article
- Obstructive sleep apnea and comorbidities: a dangerous liaison.Multidisciplinary respiratory medicine · 2019Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundMany patients with chronic obstructive pulmonary disease (COPD) suffer from poor sleep quality. We hypothesized that poor sleep quality in otherwise stable patients predicted exacerbations in these patients.
methodsThis is a secondary analysis of the results of a previously published randomized trial of azithromycin in 1,117 patients with moderate to severe COPD who were clinically stable on enrollment. Sleep quality was measured using the Pittsburgh Sleep Quality Index. Other quality of life indices included the Medical Outcome Study 36-item Short Form Health Survey and the St Georges Respiratory Questionnaire. Outcomes included time to first exacerbation and exacerbation rate.
resultsSleep quality was "poor" (Pittsburgh Sleep Quality Index >5) in 53% of participants but was not related to age or severity of airflow obstruction. Quality of life scores were worse in "poor" sleepers than in "good" sleepers. Major classes of comorbid conditions, including psychiatric, neurologic, and musculoskeletal disease, were more prevalent in the "poor" sleepers. Unadjusted time to first exacerbation was shorter (190 versus 239 days) and exacerbation rate (1.7 versus 1.37 per year) was greater in the poor sleepers, but no differences were observed after adjusting for medications and comorbid conditions associated with poor sleep.
conclusionPoor sleepers had greater exacerbation rates than did good sleepers. This appeared to be due largely to them having more, or more severe, concomitant medical conditions and taking more medications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.