ArticleSocial cognitive and affective neuroscience2015
Mothers know best: redirecting adolescent reward sensitivity toward safe behavior during risk taking.
Article in Social cognitive and affective neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
53 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Incorporating the social context into neurocognitive models of adolescent decision-making: A neuroimaging meta-analysis.Neuroscience and biobehavioral reviews · 2019Pooled it
- Resting-State Connectivity and Response to Psychotherapy Treatment in Adolescents and Adults With OCD: A Randomized Clinical Trial.The American journal of psychiatry · 2023Trial
- Multi-voxel pattern analysis for developmental cognitive neuroscientists.Developmental cognitive neuroscience · 2025Review
- Neural correlates of vicarious reward processing and peer victimization experiences in late childhood.Developmental cognitive neuroscience · 2025Article
- Depression in adolescence and young adulthood: the difficulty to integrate motivational/emotional systems.Frontiers in psychology · 2024Review
- Leveraging the developmental neuroscience of caregiving to promote resilience among youth exposed to adversity.Development and psychopathology · 2023Article
- Neural similarity in nucleus accumbens during decision-making for the self and a best friend: Links to adolescents' self-reported susceptibility to peer influence and risk taking.Human brain mapping · 2023Article
- Risk-Taking Behavior Among Male Adolescents: The Role of Observer Presence and Individual Self-Control.Journal of youth and adolescence · 2022Article
- Decision neuroscience and neuroeconomics: Recent progress and ongoing challenges.Wiley interdisciplinary reviews. Cognitive science · 2022Review
- Adolescent novelty seeking is associated with greater ventral striatal and prefrontal brain response during evaluation of risk and reward.Cognitive, affective & behavioral neuroscience · 2022Article
- Neurobiological correlates of the social and emotional impact of peer victimization: A review.Frontiers in psychiatry · 2022Review
- An exploration of amygdala-prefrontal mechanisms in the intergenerational transmission of learned fear.Developmental science · 2021Article
- Where You Lead, I Will Follow: Exploring Sibling Similarity in Brain and Behavior During Risky Decision Making.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2021Article
- Neural Correlates of Conflicting Social Influence on Adolescent Risk Taking.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2021Article
- Article
- The Development of Impulsivity and Sensation Seeking: Associations with Substance Use among At-Risk Adolescents.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2020Article
- Neural meaning making, prediction, and prefrontal-subcortical development following early adverse caregiving.Development and psychopathology · 2020Review
- Hungry for inclusion: Exposure to peer victimization and heightened social monitoring in adolescent girls.Development and psychopathology · 2020Article
- Neural Underpinnings of Social Contextual Influences on Adolescent Risk-Taking.Current addiction reports · 2020Article
- Differential Behavioral and Neural Profiles in Youth With Conduct Problems During Risky Decision-Making.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Despite being one of the healthiest developmental periods, morbidity and mortality rates increase dramatically during adolescence, largely due to preventable, risky behaviors. Heightened reward sensitivity, coupled with ineffective cognitive control, has been proposed to underlie adolescents' risk taking. In this study, we test whether reward sensitivity can be redirected to promote safe behavior. Adolescents completed a risk-taking task in the presence of their mother and alone during fMRI. Adolescents demonstrated reduced risk-taking behavior when their mothers were present compared with alone, which was associated with greater recruitment of the ventrolateral prefrontal cortex (VLPFC) when making safe decisions, decreased activation in the ventral striatum following risky decisions and greater functional coupling between the ventral striatum and VLPFC when making safe decisions. Importantly, the very same neural circuitry (i.e. ventral striatum) that has been linked to greater risk-taking can also be redirected toward thoughtful, more deliberative and safe decisions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.