Evidence map›Paper›PMID 25759440›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2015

Breakdown of the brain's functional network modularity with awareness.

Douglass Godwin, Robert L Barry, René Marois

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed.

  1. A complex network perspective on brain disease.Biological reviews of the Cambridge Philosophical Society · 2026
    Review
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  12. A mixed-modeling framework for whole-brain dynamic network analysis.Network neuroscience (Cambridge, Mass.) · 2022
    Article
  13. Article
  14. Article
  15. Mixed Modeling Frameworks for Analyzing Whole-Brain Network Data.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  16. The global neuronal workspace as a broadcasting network.Network neuroscience (Cambridge, Mass.) · 2022
    Article
  17. Review
  18. Article
  19. Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Douglass GodwinDepartment of Psychology, franklin.d.godwin@vanderbilt.edu rene.marois@vanderbilt.edu.
Robert L BarryVanderbilt University Institute of Imaging Science, Vanderbilt University, Nashville, TN 37232; and Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN 37232.
René MaroisDepartment of Psychology, Vanderbilt Vision Research Center, and Center for Integrative and Cognitive Neuroscience, Vanderbilt University, Nashville, TN 37240; franklin.d.godwin@vanderbilt.edu rene.marois@vanderbilt.edu.

Funding

Shop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI David J. Calkins · 1989 to 2026
$19.6M
Integrated Imaging of Brain Function at 7 TeslaR01EB000461 · NIBIB · VANDERBILT UNIVERSITY · PI GORE, JOHN C · 2002 to 2012
$9.4M
Functional Imaging and Resting State Connectivity in Human Spinal Cord at 7 TeslaK99EB016689 · NIBIB · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BARRY, ROBERT L · 2014 to 2015
$178k
NEI NIH HHS P30 EY008126NEI NIH HHS P30-EY008126NIBIB NIH HHS 5R01EB000461NIBIB NIH HHS K99 EB016689NIBIB NIH HHS R01 EB000461
6 · The paper itself

Abstract

Neurobiological theories of awareness propose divergent accounts of the spatial extent of brain changes that support conscious perception. Whereas focal theories posit mostly local regional changes, global theories propose that awareness emerges from the propagation of neural signals across a broad extent of sensory and association cortex. Here we tested the scalar extent of brain changes associated with awareness using graph theoretical analysis applied to functional connectivity data acquired at ultra-high field while subjects performed a simple masked target detection task. We found that awareness of a visual target is associated with a degradation of the modularity of the brain's functional networks brought about by an increase in intermodular functional connectivity. These results provide compelling evidence that awareness is associated with truly global changes in the brain's functional connectivity.

Indexed as

AwarenessNerve NetAdolescentAdultAlgorithmsBehaviorBrain MappingConsciousnessFemaleHumansMagnetic Resonance ImagingMaleModels, NeurologicalModels, StatisticalYoung Adultawarenessconsciousnessfunctional connectivitygraph theory

Identifiers

PMID25759440
PMCPMC4378398

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.