Evidence map›Paper›PMID 25759192›Full record

ArticleLegal medicine (Tokyo, Japan)2015

Ancestry informative markers for distinguishing between Thai populations based on genome-wide association datasets.

Kornkiat Vongpaisarnsin, Jennifer Beth Listman, Robert T Malison, Joel Gelernter

Open access · greenAbstract read
In one paragraph

Article in Legal medicine (Tokyo, Japan), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kornkiat VongpaisarnsinDepartment of Forensic Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. Electronic address: kornkiat.v@chula.ac.th.
Jennifer Beth ListmanDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Robert T MalisonDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA; VA Connecticut Healthcare System, West Haven Campus, West Haven, CT, USA.
Joel GelernterDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA; VA Connecticut Healthcare System, West Haven Campus, West Haven, CT, USA; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA; Department of Neurobiology, Yale University School of Medicine, New Haven, CT, USA.
Yale University · US

Funding

Drug Dependence Through the Lifespan: US-Thai Training ProgramD43TW009087 · FIC · YALE UNIVERSITY · PI GELERNTER, JOEL, MALISON, ROBERT T · 2011 to 2015
$1.1M
FIC NIH HHS D43 TW009087
6 · The paper itself

Abstract

The main purpose of this work was to identify a set of AIMs that stratify the genetic structure and diversity of the Thai population from a high-throughput autosomal genome-wide association study. In this study, more than one million SNPs from the international HapMap database and the Thai depression genome-wide association study have been examined to identify ancestry informative markers (AIMs) that distinguish between Thai populations. An efficient strategy is proposed to identify and characterize such SNPs and to test high-resolution SNP data from international HapMap populations. The best AIMs are identified to stratify the population and to infer genetic ancestry structure. A total of 124 AIMs were clearly clustered geographically across the continent, whereas only 89 AIMs stratified the Thai population from East Asian populations. Finally, a set of 273 AIMs was able to distinguish northern from southern Thai subpopulations. These markers will be of particular value in identifying the ethnic origins in regions where matching by self-reports is unavailable or unreliable, which usually occurs in real forensic cases.

Indexed as

Genome-Wide Association StudyHapMap ProjectAsian PeopleEthnicityForensic GeneticsGene FrequencyGenetic MarkersGenetics, PopulationGenotyping TechniquesHumansPolymorphism, Single NucleotidePrincipal Component AnalysisThailandGenetic MarkersAncestry informative markersForensicFstPopulationSNPThai

Identifiers

PMID25759192
PMCPMC4480199
OpenAlexW2043346464

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.